Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butyl Hydroperoxide SCHEMBL10352877 | 0.90 | ALDH1A1 (0.39) | ALDH1A1TSHRTDP1 | |
| Tert-Butyl Hydroperoxide SCHEMBL20163 | 0.90 | — | — | |
| Tert-Butyl Hydroperoxide SCHEMBL11312020 | 0.90 | — | — | |
| Tert-Butyl Hydroperoxide SCHEMBL3026366 | 0.90 | — | — | |
| Tert-Butyl Hydroperoxide SCHEMBL6896488 | 0.90 | ALDH1A1 (0.39) | ALDH1A1TSHRTDP1 | |
| Tert-Butyl Hydroperoxide SCHEMBL9562915 | 0.79 | TDP1 (0.31) | ALDH1A1TSHRTDP1 | |
| Tert-Butyl Hydroperoxide SCHEMBL9817088 | 0.76 | — | — | |
| Tert-Butyl Hydroperoxide SCHEMBL9310973 | 0.71 | — | — | |
| SCHEMBL6456965 | 0.60 | TSHR (0.30) | TSHR | |
| SCHEMBL1697134 | 0.57 | ALDH1A1 (0.36) | ALDH1A1TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100041905-A1 | Process for the Preparation of Substituted 2-Acetylamino-Alkoxyphenyl | ASTRAZENECA AB (SE) | 2010-02-18 | — | — | US | disclosed |
| CN-101516863-A | Process for preparing substituted 2-acetylamino-alkoxybenzenes | ASTRAZENECA AB (SE) | 2009-08-26 | — | — | CN | disclosed |
| EP-2044045-A2 | A PROCESS FOR THE PREPARATION OF SUBSTITUTED 2-ACETYLAMINO-ALKOXYPHENYL | AstraZeneca AB (SE) | 2009-04-08 | — | — | EP | disclosed |
| WO-2008010764-A2 | A PROCESS FOR THE PREPARATION OF SUBSTITUTED 2-ACETYLAMINO-ALKOXYPHENYL | ASTRAZENECA AB (SE) | 2008-01-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100041905-A1 | Process for the Preparation of Substituted 2-Acetylamino-Alkoxyphenyl | F12, RPS4Y1, CCNA1 | ALDH1A1 126/4885TSHR 862/4885TDP1 3188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.