Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Arginine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 2/20 | 0.38 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.38 |
| ▸ | NPY4R | P50391 | 6/20 | 0.35 |
| ▸ | NPY1R | P25929 | 5/20 | 0.35 |
| ▸ | NPY2R | P49146 | 4/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.35 |
| ▸ | OTC | P00480 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 2/20 | 0.34 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.34 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 3/20 | 0.33 |
| ▸ | NOS3 | P29474 | 2/20 | 0.33 |
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Arginine SCHEMBL28419523 | 1.00 | PRCP (0.38) | PRCPSLC7A5NPY4RNPY1RNPY2R | |
| Arginine SCHEMBL2459501 | 0.98 | PRCP (0.37) | PRCPSLC7A5NPY4RNPY1RNPY2R | |
| Arginine SCHEMBL8628358 | 0.96 | PRCP (0.35) | PRCPSLC7A5NPY4RNPY1RNPY2R | |
| Arginine SCHEMBL9480236 | 0.96 | PRCP (0.35) | PRCPSLC7A5NPY4RNPY1RNPY2R | |
| Arginine SCHEMBL28552748 | 0.96 | PRCP (0.35) | PRCPSLC7A5NPY4RNPY1RNPY2R | |
| Arginine SCHEMBL27883095 | 0.96 | PRCP (0.35) | PRCPSLC7A5NPY4RNPY1RNPY2R | |
| Arginine SCHEMBL29255555 | 0.96 | PRCP (0.35) | PRCPSLC7A5NPY4RNPY1RNPY2R | |
| Arginine SCHEMBL29157307 | 0.95 | PRCP (0.35) | PRCPSLC7A5NPY4RNPY1RNPY2R | |
| Arginine SCHEMBL4278540 | 0.95 | PRCP (0.35) | PRCPSLC7A5NPY4RNPY1RNPY2R | |
| Arginine SCHEMBL1551248 | 0.93 | PRCP (0.35) | PRCPSLC7A5NPY4RNPY1RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140315278-A1 | SPORE SURFACE DISPLAYS OF BIOACTIVE MOLECULES | DSM IP ASSETS B.V. (NL) | 2014-10-23 | — | — | US | disclosed |
| US-20130216653-A1 | SPORE SURFACE DISPLAY OF BIOACTIVE MOLECULES | DSM IP ASSETS B.V. (NL) | 2013-08-22 | — | — | US | disclosed |
| EP-2588614-A1 | SPORE SURFACE DISPLAY OF BIOACTIVE MOLECULES | DSM IP Assets B.V. (NL) | 2013-05-08 | — | — | EP | disclosed |
| WO-2012001000-A1 | SPORE SURFACE DISPLAY OF BIOACTIVE MOLECULES | DSM IP ASSETS B.V. (NL) | 2012-01-05 | — | — | WO | disclosed |
| US-20100055244-A1 | SPORE SURFACE DISPLAYS OF BIOACTIVE MOLECULES | DSM IP ASSETS B.V. (NL) | 2010-03-04 | — | — | US | disclosed |
| EP-2049669-A2 | SPORE SURFACE DISPLAYS OF BIOACTIVE MOLECULES | DSMIP Assets B.V. (NL) | 2009-04-22 | — | — | EP | disclosed |
| WO-2008017483-A2 | SPORE SURFACE DISPLAYS OF BIOACTIVE MOLECULES | DSM IP ASSETS B.V. (NL) | 2008-02-14 | — | — | WO | disclosed |
| EP-0873404-B1 | ANGIOTENSIN CONVERTING ENZYME INHIBITORS | NONG SIM CO LTD (KR) | 2003-04-16 | — | — | EP | disclosed |
| US-6232438-B1 | TRIPEPTIDE HISTIDINE-HISTIDINE-LEUCINE; DERIVED FROM FERMENTED SOYBEAN PASTE FOR CONTROLLING HYPERTENSION; EXHIBITS SIMILAR OR HIGHER ACTIVITIES | NONG SHIM CO., LTD. (KR) | 2001-05-15 | — | — | US | disclosed |
| EP-0873404-A1 | ANGIOTENSIN CONVERTING ENZYME INHIBITORS | Nong Shim Co., Ltd. (KR) | 1998-10-28 | — | — | EP | disclosed |
| WO-1997025418-A1 | ANGIOTENSIN CONVERTING ENZYME INHIBITORS | NONG SHIM CO., LTD. (KR) | 1997-07-17 | — | — | WO | disclosed |