Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.76 |
| ▸ | MCHR1 | Q99705 | 15/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | ATR | Q13535 | 2/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16972703 | 0.86 | KCNH2 (1.00) | KCNH2MCHR1 | |
| SCHEMBL16972681 | 0.85 | KCNH2 (0.69) | KCNH2MCHR1 | |
| SCHEMBL16972689 | 0.83 | KCNH2 (0.77) | KCNH2MCHR1 | |
| SCHEMBL14741162 | 0.80 | KCNH2 (0.48) | KCNH2MCHR1 | |
| SCHEMBL16984188 | 0.76 | KCNH2 (0.52) | KCNH2PIK3CAMTOR | |
| SCHEMBL16984241 | 0.73 | KCNH2 (0.76) | KCNH2 | |
| SCHEMBL16972717 | 0.73 | KCNH2 (0.76) | KCNH2 | |
| SCHEMBL16984185 | 0.72 | KCNH2 (0.75) | KCNH2MCHR1 | |
| SCHEMBL16984195 | 0.72 | KCNH2 (0.73) | KCNH2MCHR1 | |
| SCHEMBL16972707 | 0.72 | KCNH2 (0.73) | KCNH2MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015114317-A1 | 5H-ISOTHIAZOLO[4,5-C]PYRIDINE-3,4-DIONE OR 5H-PYRAZOLO[4,3-C]PYRIDIN-3,4-DIONE AS ANTIBACTERIAL COMPOUNDS | REDX PHARMA PLC (GB) | 2015-08-06 | — | — | WO | disclosed |
| WO-2015114317-A1 | 5H-ISOTHIAZOLO[4,5-C]PYRIDINE-3,4-DIONE OR 5H-PYRAZOLO[4,3-C]PYRIDIN-3,4-DIONE AS ANTIBACTERIAL COMPOUNDS | REDX PHARMA PLC (GB) | 2015-08-06 | — | — | WO | disclosed |