Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.64 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | KMT5A | Q9NQR1 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16972673 | 0.95 | KCNH2 (0.66) | KCNH2HRH3CHRNA7 | |
| SCHEMBL16984241 | 0.79 | KCNH2 (0.76) | KCNH2 | |
| SCHEMBL16972717 | 0.79 | KCNH2 (0.76) | KCNH2 | |
| SCHEMBL16984195 | 0.78 | KCNH2 (0.73) | KCNH2HRH3 | |
| SCHEMBL16972703 | 0.78 | KCNH2 (1.00) | KCNH2 | |
| SCHEMBL16972707 | 0.78 | KCNH2 (0.73) | KCNH2HRH3 | |
| SCHEMBL16984191 | 0.77 | KCNH2 (0.72) | KCNH2 | |
| SCHEMBL16972700 | 0.75 | KCNH2 (0.64) | KCNH2 | |
| SCHEMBL16972693 | 0.73 | KCNH2 (0.61) | KCNH2 | |
| SCHEMBL16972695 | 0.73 | KCNH2 (0.61) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015114317-A1 | 5H-ISOTHIAZOLO[4,5-C]PYRIDINE-3,4-DIONE OR 5H-PYRAZOLO[4,3-C]PYRIDIN-3,4-DIONE AS ANTIBACTERIAL COMPOUNDS | REDX PHARMA PLC (GB) | 2015-08-06 | — | — | WO | disclosed |
| WO-2015114317-A1 | 5H-ISOTHIAZOLO[4,5-C]PYRIDINE-3,4-DIONE OR 5H-PYRAZOLO[4,3-C]PYRIDIN-3,4-DIONE AS ANTIBACTERIAL COMPOUNDS | REDX PHARMA PLC (GB) | 2015-08-06 | — | — | WO | disclosed |