Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 2/20 | 0.34 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.34 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.33 |
| ▸ | ALPG | P10696 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | WDR5 | P61964 | 3/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16759985 | 0.83 | PHF8 (0.45) | ALPLPLAAPHF8ALPGWDR5 | |
| SCHEMBL24496307 | 0.68 | AR (0.32) | AR | |
| SCHEMBL27028541 | 0.66 | GRIN2D (0.31) | — | |
| SCHEMBL30695452 | 0.64 | ALDH1A1 (0.39) | IRAK4 | |
| SCHEMBL19924875 | 0.62 | BRD4 (0.40) | PHF8WDR5KDM4CAR | |
| Bromide SCHEMBL6369788 | 0.62 | ALPL (0.41) | ALPLPLAAALPG | |
| SCHEMBL30961358 | 0.62 | KDM2B (0.44) | ALPLPLAAPHF8ALPGAR | |
| SCHEMBL24977412 | 0.62 | ALPL (0.37) | ALPLPLAAALPG | |
| SCHEMBL2378140 | 0.60 | PHF8 (0.45) | PHF8WDR5KDM4C | |
| SCHEMBL22854663 | 0.60 | PHF8 (0.45) | PHF8WDR5KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3099672-A1 | FUSED IMIDAZOLE COMPOUNDS | ONO Pharmaceutical Co., Ltd. (JP) | 2016-12-07 | — | — | EP | disclosed |
| WO-2015115673-A1 | FUSED IMIDAZOLE COMPOUNDS | ONO PHARMACEUTICAL CO., LTD. (JP) | 2015-08-06 | — | — | WO | disclosed |