Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | DCTPP1 | Q9H773 | 7/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31539799 | 0.85 | GRIN2D (0.41) | TSHRALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL27942973 | 0.85 | GRIN2D (0.41) | TSHRALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL31539724 | 0.80 | TSHR (0.54) | TSHRALDH1A1DCTPP1GRIN2DGRIN3B | |
| SCHEMBL6833235 | 0.78 | TSHR (0.52) | TSHRALDH1A1DCTPP1GRIN2DGRIN3B | |
| SCHEMBL30225936 | 0.77 | TSHR (0.50) | TSHRALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL209310 | 0.77 | TSHR (0.50) | TSHRALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL17767940 | 0.73 | GRIN2D (0.41) | TSHRALDH1A1DCTPP1GRIN2DGRIN3B | |
| SCHEMBL2972185 | 0.73 | ALDH1A1 (0.44) | TSHRALDH1A1TDP1MAPTMEN1 | |
| SCHEMBL27318752 | 0.72 | MAPT (0.42) | ALDH1A1MAPTMEN1KMT2APKM | |
| SCHEMBL11714399 | 0.72 | CYP1A2 (0.43) | TSHRALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3099672-A1 | FUSED IMIDAZOLE COMPOUNDS | ONO Pharmaceutical Co., Ltd. (JP) | 2016-12-07 | — | — | EP | disclosed |
| WO-2015115673-A1 | FUSED IMIDAZOLE COMPOUNDS | ONO PHARMACEUTICAL CO., LTD. (JP) | 2015-08-06 | — | — | WO | disclosed |