Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.40 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | AR | P10275 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9753804 | 0.83 | ALDH1A1 (0.42) | MAPTALDH1A1NPC1MAPK1POLB | |
| SCHEMBL9270724 | 0.77 | POLB (0.47) | MAPTALDH1A1NPC1NPSR1MAPK1 | |
| SCHEMBL30593158 | 0.76 | POLB (0.42) | MAPTALDH1A1NPC1NPSR1HTT | |
| SCHEMBL11628165 | 0.76 | POLB (0.42) | MAPTALDH1A1NPC1NPSR1HTT | |
| SCHEMBL30101777 | 0.76 | ALDH1A1 (0.44) | MAPTALDH1A1NPC1NPSR1XBP1 | |
| SCHEMBL11728849 | 0.74 | KDM4E (0.46) | MAPTALDH1A1NPC1NPSR1TP53 | |
| SCHEMBL22445772 | 0.73 | ALDH1A1 (0.48) | MAPTALDH1A1NPC1NPSR1HTT | |
| SCHEMBL574989 | 0.72 | ALDH1A1 (0.49) | MAPTALDH1A1NPC1NPSR1XBP1 | |
| SCHEMBL30846439 | 0.72 | ALDH1A1 (0.49) | MAPTALDH1A1NPC1NPSR1XBP1 | |
| SCHEMBL27314724 | 0.72 | ALDH1A1 (0.49) | MAPTALDH1A1NPC1NPSR1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1031053-C | Azaoxindole derivatives | PFIZER (US) | 1996-02-21 | — | — | CN | disclosed |
| CN-1053065-A | AZAOXINDOLE DERIVATIVES | PFIZER (US) | 1991-07-17 | — | — | CN | disclosed |