Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5575317 | 0.76 | POLB (0.59) | TSHRKMT2AMEN1L3MBTL1GAA | |
| SCHEMBL3192032 | 0.76 | POLB (0.59) | TSHRKMT2AMEN1L3MBTL1GAA | |
| SCHEMBL98457 | 0.76 | POLB (0.59) | TSHRKMT2AMEN1L3MBTL1GAA | |
| SCHEMBL223631 | 0.76 | POLB (0.59) | TSHRKMT2AMEN1L3MBTL1GAA | |
| SCHEMBL6206953 | 0.76 | POLB (0.59) | TSHRKMT2AMEN1L3MBTL1GAA | |
| SCHEMBL1697307 | 0.74 | CHRNB2 (0.42) | — | |
| SCHEMBL1697295 | 0.74 | CHRNB2 (0.42) | — | |
| Hydrochloric Acid SCHEMBL1697308 | 0.73 | CHRNB2 (0.41) | — | |
| SCHEMBL1697301 | 0.68 | EPHX2 (0.34) | KMT2AMEN1ALDH1A1NPSR1HTT | |
| SCHEMBL14214024 | 0.66 | POLB (0.66) | TSHRKMT2AMEN1L3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011149862-A1 | NICOTINIC RECEPTOR NON-COMPETITIVE ANTAGONISTS MODULATORS | TARGACEPT, INC. (US) | 2011-12-01 | — | — | WO | disclosed |