Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.59 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.59 |
| ▸ | ESR1 | P03372 | 3/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5699144 | 0.90 | GABRA1 (0.51) | GABRA1GABRB2ESR1ESR2SLC7A5 | |
| SCHEMBL1899586 | 0.87 | ESR1 (0.68) | GABRA1GABRB2ESR1ESR2TRPA1 | |
| SCHEMBL11193682 | 0.85 | TYR (0.49) | GABRA1GABRB2ESR1ESR2TRPA1 | |
| SCHEMBL23978973 | 0.82 | ESR1 (0.47) | GABRA1GABRB2ESR1ESR2TRPA1 | |
| SCHEMBL11584588 | 0.82 | ALDH1A1 (0.50) | GABRA1GABRB2ESR1ESR2TRPA1 | |
| SCHEMBL27571821 | 0.82 | MEN1 (0.54) | GABRA1GABRB2TRPA1ALOX15ALOX12 | |
| SCHEMBL11702823 | 0.82 | KDM4E (0.46) | GABRA1GABRB2ESR1ESR2SLC7A5 | |
| SCHEMBL9153914 | 0.81 | ESR1 (0.46) | GABRA1GABRB2ESR1ESR2TRPA1 | |
| SCHEMBL1952363 | 0.80 | SLC6A2 (0.47) | ESR1ESR2TRPA1MAPK1CYP3A4 | |
| SCHEMBL25215353 | 0.80 | SLC6A2 (0.47) | ESR1ESR2TRPA1MAPK1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3099284-A1 | OIL-IN-WATER EMULSION SUNSCREEN COMPOSITION | ISP Investments Inc. (US) | 2016-12-07 | — | — | EP | claimed |
| WO-2015116899-A1 | OIL-IN -WATER EMULSION SUNSCREEN COMPOSITION | ISP INVESTMENTS INC. (US) | 2015-08-06 | — | — | WO | claimed |