SCHEMBL16974428

SCHEMBL16974428

NC(O)(CC1CCCC1)C1CCCC1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM2 Q14416 1/20 0.37
GRM3 Q14832 1/20 0.37
SIGMAR1 Q99720 1/20 0.32
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
USP2 O75604 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
ALOX15 P16050 1/20 0.31
ALOX12 P18054 1/20 0.31
BRCA1 P38398 1/20 0.31
HTT P42858 1/20 0.31
RECQL P46063 1/20 0.31
KMT2A Q03164 1/20 0.31
HSD17B10 Q99714 1/20 0.31
METAP1 P53582 1/20 0.31
ALOX5 P09917 1/20 0.30
CYP1A2 P05177 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16974430 0.98 GRM2 (0.40) GRM2GRM3SIGMAR1KDM4EMEN1
SCHEMBL8819154 0.75 GRM2 (0.43) GRM2GRM3SIGMAR1KDM4EMEN1
SCHEMBL16616932 0.73 CYP1A2 (0.36) GRM2GRM3SIGMAR1HPGDKMT2A
SCHEMBL8518913 0.73 CYP1A2 (0.36) GRM2GRM3SIGMAR1HPGDKMT2A
SCHEMBL4001798 0.73 SIGMAR1 (0.38) GRM2GRM3SIGMAR1KDM4EMEN1
SCHEMBL601051 0.73 CYP1A2 (0.36) GRM2GRM3SIGMAR1HPGDKMT2A
SCHEMBL4977291 0.71 CYP1A2 (0.34) MEN1ALDH1A1LMNAALOX12KMT2A
SCHEMBL11695758 0.71 GRM2 (0.41) GRM2GRM3SIGMAR1KDM4EMEN1
Bromide SCHEMBL11227539 0.71 GRM2 (0.37) GRM2GRM3SIGMAR1KDM4EMEN1
SCHEMBL2421111 0.71 GRM2 (0.41) GRM2GRM3SIGMAR1KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2928992-B1 ADDITIVE COMPOSITIONS AND INDUSTRIAL PROCESS FLUIDS FUCHS PETROLUB SE (DE) 2018-08-01 EP claimed
US-9587197-B2 Additive compositions and industrial process fluids FUCHS PETROLUB SE (DE) 2017-03-07 US claimed
US-20160201000-A1 ADDITIVE COMPOSITIONS AND INDUSTRIAL PROCESS FLUIDS FUCHS PETROLUB SE (DE) 2016-07-14 US claimed
EP-2928992-A1 ADDITIVE COMPOSITIONS AND INDUSTRIAL PROCESS FLUIDS Fuchs Petrolub SE (DE) 2015-10-14 EP claimed
WO-2015116233-A1 ADDITIVE COMPOSITIONS AND INDUSTRIAL PROCESS FLUIDS FUCHS PETROLUB SE (DE) 2015-08-06 WO claimed
EP-2928992-B1 ADDITIVE COMPOSITIONS AND INDUSTRIAL PROCESS FLUIDS FUCHS PETROLUB SE (DE) 2018-08-01 EP disclosed
US-9587197-B2 Additive compositions and industrial process fluids FUCHS PETROLUB SE (DE) 2017-03-07 US disclosed
US-20160201000-A1 ADDITIVE COMPOSITIONS AND INDUSTRIAL PROCESS FLUIDS FUCHS PETROLUB SE (DE) 2016-07-14 US disclosed
EP-2928992-A1 ADDITIVE COMPOSITIONS AND INDUSTRIAL PROCESS FLUIDS Fuchs Petrolub SE (DE) 2015-10-14 EP disclosed
WO-2015116233-A1 ADDITIVE COMPOSITIONS AND INDUSTRIAL PROCESS FLUIDS FUCHS PETROLUB SE (DE) 2015-08-06 WO disclosed