Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.58 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.56 |
| ▸ | HTR3A | P46098 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.50 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.50 |
| ▸ | ITGAV | P06756 | 1/20 | 0.50 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.50 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2747664 | 1.00 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2MAPK1KDM4ENPSR1 | |
| SCHEMBL5259296 | 1.00 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2MAPK1KDM4ENPSR1 | |
| SCHEMBL7871674 | 0.90 | SMN1; SMN2 (0.82) | ALDH1A1SMN1; SMN2MAPK1KDM4ENPSR1 | |
| SCHEMBL4602203 | 0.88 | ALDH1A1 (0.78) | ALDH1A1SMN1; SMN2MAPK1KDM4ENPSR1 | |
| SCHEMBL1697444 | 0.88 | ALDH1A1 (0.78) | ALDH1A1SMN1; SMN2MAPK1KDM4ENPSR1 | |
| SCHEMBL11424044 | 0.87 | ALDH1A1 (0.76) | ALDH1A1SMN1; SMN2MAPK1KDM4ENPSR1 | |
| SCHEMBL28617751 | 0.84 | SMN1; SMN2 (0.72) | ALDH1A1SMN1; SMN2MAPK1KDM4ENPSR1 | |
| SCHEMBL2748801 | 0.83 | ALDH1A1 (0.71) | ALDH1A1SMN1; SMN2MAPK1KDM4ENPSR1 | |
| SCHEMBL7429992 | 0.82 | ALDH1A1 (0.69) | ALDH1A1SMN1; SMN2MAPK1KDM4ENPSR1 | |
| SCHEMBL5697246 | 0.81 | ALDH1A1 (0.68) | ALDH1A1SMN1; SMN2MAPK1KDM4ENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012004811-A1 | PROCESS FOR THE PREPARATION OF 5-SUBSTSITUTED INDOLE DERIVATIVE | IND-SWIFT LABORATORIES LIMITED (IN) | 2012-01-12 | — | — | WO | disclosed |