Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16975093 | 0.89 | PDPK1 (0.49) | HTTPDPK1KDM4EGAALMNA | |
| SCHEMBL3100667 | 0.85 | PDPK1 (0.56) | HTTPDPK1KDM4EGAALMNA | |
| SCHEMBL3102508 | 0.84 | PDPK1 (0.57) | HTTPDPK1KDM4EGAALMNA | |
| SCHEMBL16975043 | 0.83 | PDPK1 (0.51) | HTTPDPK1KDM4EGAALMNA | |
| SCHEMBL3102176 | 0.80 | PDPK1 (0.59) | HTTPDPK1KDM4EGAALMNA | |
| SCHEMBL3114173 | 0.77 | PDPK1 (0.59) | HTTPDPK1KDM4EGAALMNA | |
| SCHEMBL3103014 | 0.76 | PDPK1 (0.50) | HTTPDPK1KDM4EGAALMNA | |
| SCHEMBL16982857 | 0.72 | PDPK1 (0.70) | HTTPDPK1KDM4EGAALMNA | |
| SCHEMBL7919295 | 0.72 | PDPK1 (0.54) | HTTPDPK1KDM4EGAALMNA | |
| SCHEMBL3095187 | 0.70 | TMIGD3 (0.69) | HTTPDPK1KDM4EGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015114663-A1 | NOVEL THIENO [2,3-D]PYRIMIDIN-4(3H)-ONE COMPOUNDS WITH ANTIMYCOBACTERIAL PROPERTIES | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-08-06 | — | — | WO | claimed |