Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.57 |
| ▸ | PKM | P14618 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | F2 | P00734 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | SRC | P12931 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | GPR3 | P46089 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7482958 | 0.86 | MCL1 (0.52) | KMT2APKMMAPTALDH1A1NPSR1 | |
| SCHEMBL12868409 | 0.85 | ALDH1A1 (0.46) | KMT2APKMMAPTALDH1A1NPSR1 | |
| SCHEMBL11420999 | 0.81 | ALDH1A1 (0.65) | KMT2APKMMAPTALDH1A1NPSR1 | |
| SCHEMBL12883765 | 0.81 | TSHR (0.55) | KMT2APKMMAPTALDH1A1NPSR1 | |
| SCHEMBL17484805 | 0.80 | TSHR (0.66) | KMT2APKMMAPTALDH1A1NPSR1 | |
| SCHEMBL4106684 | 0.75 | EGFR (0.68) | KMT2AMAPTALDH1A1NPSR1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL8687498 | 0.75 | NPC1 (0.42) | KMT2AMAPTALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL5001736 | 0.73 | ALDH1A1 (0.54) | KMT2APKMMAPTALDH1A1L3MBTL1 | |
| SCHEMBL7673745 | 0.73 | EGFR (0.42) | KMT2AMAPTALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL7278316 | 0.73 | EGFR (0.65) | KMT2AMAPTALDH1A1L3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9096518-B2 | Substituted hydroxamic acids and uses thereof | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2015-08-04 | — | — | US | disclosed |