Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | ESR1 | P03372 | 5/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12090539 | 1.00 | TDP1 (0.57) | TDP1CYP3A4ESR1ESR2TSHR | |
| SCHEMBL1093877 | 0.90 | TSHR (0.52) | TDP1CYP3A4TSHRLMNATYR | |
| Phosphoric Acid SCHEMBL31576074 | 0.88 | ESR1 (0.45) | TDP1CYP3A4ESR1ESR2LMNA | |
| SCHEMBL29507318 | 0.84 | TRPV1 (0.46) | TDP1CYP3A4ESR1ESR2LMNA | |
| SCHEMBL14422422 | 0.84 | TRPV1 (0.46) | TDP1CYP3A4LMNARAB9ANPC1 | |
| SCHEMBL2154715 | 0.82 | L3MBTL1 (0.42) | TDP1TSHRLMNATYRALDH1A1 | |
| SCHEMBL2153480 | 0.82 | TSHR (0.41) | TDP1CYP3A4ESR1ESR2TSHR | |
| SCHEMBL28521706 | 0.82 | CYP3A4 (0.52) | TDP1CYP3A4ESR1ESR2TSHR | |
| SCHEMBL4978017 | 0.82 | CYP3A4 (0.52) | TDP1CYP3A4ESR1ESR2TSHR | |
| Hydrochloric Acid SCHEMBL8206111 | 0.82 | ESR1 (0.54) | TDP1CYP3A4ESR1ESR2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9896461-B2 | Polysilylated organosilane compounds | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S) (FR) | 2018-02-20 | — | — | US | disclosed |
| US-9896461-B2 | Polysilylated organosilane compounds | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S) (FR) | 2018-02-20 | — | — | US | disclosed |
| US-20150218192-A1 | Polysilylated Organosilane Compounds | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) | 2015-08-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150218192-A1 | Polysilylated Organosilane Compounds | ALG8, UGT1A9, SI | TDP1 2224/4885CYP3A4 214/4885ESR1 3657/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.