Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MMP13 | P45452 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | ACR | P10323 | 3/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.37 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16979799 | 0.97 | TDP1 (0.43) | TDP1KMT2AMEN1ESR1ESR2 | |
| SCHEMBL16979798 | 0.92 | ESR1 (0.46) | TDP1KMT2AMEN1MMP13ESR1 | |
| SCHEMBL16979792 | 0.92 | TDP1 (0.43) | TDP1KMT2AMEN1MMP13ACR | |
| SCHEMBL16979790 | 0.89 | HIF1A (0.39) | TDP1KMT2AESR1ESR2ALDH1A1 | |
| SCHEMBL16979808 | 0.89 | ESR1 (0.49) | TDP1KMT2AMEN1ESR1ESR2 | |
| SCHEMBL16979806 | 0.88 | TDP1 (0.47) | TDP1KMT2AMEN1ACRPRSS1 | |
| SCHEMBL16979785 | 0.88 | MMP13 (0.42) | TDP1KMT2AMEN1MMP13ACR | |
| SCHEMBL16979809 | 0.87 | TDP1 (0.46) | TDP1KMT2AMEN1MMP13ACR | |
| SCHEMBL16979788 | 0.86 | KMT2A (0.39) | TDP1KMT2AMEN1ESR1ESR2 | |
| SCHEMBL16979784 | 0.85 | TDP1 (0.46) | TDP1KMT2AMEN1MMP13ACR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9778581-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2017-10-03 | — | — | US | disclosed |
| US-9665020-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2017-05-30 | — | — | US | disclosed |
| US-20150277249-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2015-10-01 | — | — | US | disclosed |
| US-20150220007-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2015-08-06 | — | — | US | disclosed |