⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6251607 | 0.96 | — | — | |
| SCHEMBL5212661 | 0.85 | — | — | |
| Malonic Acid SCHEMBL29116689 | 0.80 | LDHA (0.75) | — | |
| SCHEMBL125404 | 0.79 | — | — | |
| Malonic Acid SCHEMBL6923127 | 0.77 | LDHA (0.69) | — | |
| Ammonia Solution, Strong SCHEMBL27404985 | 0.75 | — | — | |
| Malonic Acid SCHEMBL1332554 | 0.74 | — | — | |
| Malonic Acid SCHEMBL336 | 0.74 | — | — | |
| Malonic Acid SCHEMBL1332405 | 0.74 | — | — | |
| Malonic Acid SCHEMBL23831 | 0.74 | LDHA (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 287 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3596054-B1 | 5-CARBOXAMIDE-2-THIOBARBITURIC ACIDS AND USE THEREOF AS MEDICAMENTS | FONDAZIONE ST ITALIANO TECNOLOGIA (IT) | 2021-01-27 | — | — | EP | claimed |
| EP-2943468-B1 | A NOVEL PROCESS FOR THE PREPARATION OF N-(4-NITRO-2-SULFAMOYL-PHENYL)-MALONAMIC ACID METHYL ESTER AND N-(4-AMINO-2-SULFAMOYL-PHENYL)-MALONAMIC ACID METHYL ESTER | HOFFMANN LA ROCHE (CH) | 2017-03-01 | — | — | EP | claimed |
| CN-104961758-A | Chain musk odorant and preparation method thereof | ZHENGZHOU TOBACCO RES CNTC | 2015-10-07 | — | — | CN | claimed |
| EP-0367131-B1 | Light-sensitive composition | BASF AG (DE) | 1995-02-22 | — | — | EP | claimed |
| EP-4735431-A2 | MK2 INHIBITORS AND METHODS OF MAKING AND USING THE SAME | GILEAD SCIENCES, INC. (US) | 2026-05-06 | — | — | EP | disclosed |
| WO-2025006568-A2 | MK2 INHIBITORS AND METHODS OF MAKING AND USING THE SAME | GILEAD SCIENCES, INC. (US) | 2025-01-02 | — | — | WO | disclosed |
| US-20240409556-A1 | BENZOPIPERAZINE AND RELATED ANALOGS FOR INHIBITING YAP/TAZ-TEAD | SPRINGWORKS THERAPEUTICS, INC. | 2024-12-12 | — | — | US | disclosed |
| EP-4402126-A1 | AHR AGONISTS | Eli Lilly and Company (US) | 2024-07-24 | — | — | EP | disclosed |
| US-12037322-B2 | AHR agonists | ELI LILLY AND COMPANY (US) | 2024-07-16 | — | — | US | disclosed |
| CN-118215654-A | AHR agonists | 伊莱利利公司 | 2024-06-18 | — | — | CN | disclosed |
| US-11912714-B2 | Spiropyrrolidine derived antiviral agents | ENANTA PHARMACEUTICALS, INC. (US) | 2024-02-27 | — | — | US | disclosed |
| CN-111032643-B | Quinolinone compounds | 詹森药业有限公司 | 2023-05-30 | — | — | CN | disclosed |
| EP-0082712-A2 | 2-Phenylimidazo(2,1-b)benzothiazole compounds, salts thereof, process for producing them, and pharmaceutical compositions containing them | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1983-06-29 | — | — | EP | disclosed |
| EP-0072743-A1 | 1,2-Dithiol-3-ylidene ammonium derivatives, process for their preparation and medicines containing them | RHONE-POULENC SANTE (FR) | 1983-02-23 | — | — | EP | disclosed |
| EP-0063509-A1 | 2-Piperazino-pyrimidine derivatives, processes for their preparation, medicaments containing them and their use as intermediates in the manufacture of medicaments | PHARMUKA LABORATOIRES (FR) | 1982-10-27 | — | — | EP | disclosed |
| US-4336380-A | FOR USE AS HYPOTENSIVE AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1982-06-22 | — | — | US | disclosed |
| US-4296236-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1981-10-20 | — | — | US | disclosed |
| US-4278793-A | ANTIBIOTICS, BACTERICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-07-14 | — | — | US | disclosed |
| US-4276417-A | TREATMENT OF VASCULAR-CONDITION HYPERTENSION | HOFFMANN-LA ROCHE INC. (US) | 1981-06-30 | — | — | US | disclosed |
| US-3965118-A | Lactone intermediates | THE UPJOHN COMPANY (US) | 1976-06-22 | — | — | US | disclosed |