Clopyralid

Clopyralid

SCHEMBL1698170

CN.O=C(O)c1nc(Cl)ccc1Cl

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.47
MEN1 O00255 3/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
HSD17B10 Q99714 1/20 0.47
ALDH1A1 P00352 3/20 0.46
GAA P10253 2/20 0.46
CTSA P10619 2/20 0.43
KDM4E B2RXH2 1/20 0.42
L3MBTL1 Q9Y468 2/20 0.41
TDP1 Q9NUW8 1/20 0.41
LMNA P02545 1/20 0.40
MAPT P10636 1/20 0.40
CRHBP P24387 1/20 0.39
CRHR2 Q13324 1/20 0.39
NAPRT Q6XQN6 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Clopyralid SCHEMBL8535196 0.94 KMT2A (0.50) KMT2AMEN1CYP2C9CYP2C19HSD17B10
Clopyralid SCHEMBL29371357 0.94 KMT2A (0.50) KMT2AMEN1CYP2C9CYP2C19HSD17B10
Clopyralid SCHEMBL54779 0.94 KMT2A (0.50) KMT2AMEN1CYP2C9CYP2C19HSD17B10
Clopyralid SCHEMBL726319 0.91 KMT2A (0.49) KMT2AMEN1CYP2C9CYP2C19HSD17B10
Clopyralid SCHEMBL5934004 0.91 KMT2A (0.49) KMT2AMEN1CYP2C9CYP2C19HSD17B10
Clopyralid SCHEMBL29256280 0.91 KMT2A (0.49) KMT2AMEN1CYP2C9CYP2C19HSD17B10
Clopyralid SCHEMBL20377277 0.91 KMT2A (0.49) KMT2AMEN1CYP2C9CYP2C19HSD17B10
Clopyralid SCHEMBL2403527 0.91 KMT2A (0.49) KMT2AMEN1CYP2C9CYP2C19HSD17B10
Clopyralid SCHEMBL11270195 0.91 KMT2A (0.49) KMT2AMEN1CYP2C9CYP2C19HSD17B10
Clopyralid SCHEMBL27890715 0.90 L3MBTL1 (0.45) KMT2AMEN1CYP2C9CYP2C19HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2582240-B1 HERBICIDAL PICOLINIC ACID SALT COMPOSITION NUFARM AUSTRALIA LTD (AU) 2016-03-16 EP claimed
US-8865625-B2 Herbicidal picolinic acid salt composition NUFARM AUSTRALIA LIMITED (AU) 2014-10-21 US claimed
US-20130157862-A1 HERBICIDAL PICOLINIC ACID SALT COMPOSITION NUFARM AUSTRALIA LIMITED (AU) 2013-06-20 US claimed
EP-2582240-A1 HERBICIDAL PICOLINIC ACID SALT COMPOSITION Nufarm Australia Limited (AU) 2013-04-24 EP claimed
WO-2011160162-A1 HERBICIDAL PICOLINIC ACID SALT COMPOSITION NUFARM AUSTRALIA LIMITED (AU) 2011-12-29 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130157862-A1 HERBICIDAL PICOLINIC ACID SALT COMPOSITION MTX2, DDT, MTX1 KMT2A 191/4885MEN1 1950/4885CYP2C9 646/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.