Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.42 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16982287 | 0.86 | LIMK1 (0.31) | GPR3LIMK1SMN1; SMN2POLB | |
| SCHEMBL16982290 | 0.76 | LIMK1 (0.39) | GPR3LIMK1CDK5CDK5R1MAPT | |
| SCHEMBL4828993 | 0.72 | GPR3 (0.45) | GPR3LIMK1CDK5CDK5R1RAB9A | |
| SCHEMBL24056925 | 0.72 | GPR3 (0.48) | GPR3LIMK1CDK5CDK5R1KDM4E | |
| SCHEMBL16693485 | 0.72 | GPR3 (0.48) | GPR3LIMK1CDK5CDK5R1KDM4E | |
| SCHEMBL15747056 | 0.72 | GPR3 (0.48) | GPR3LIMK1CDK5CDK5R1KDM4E | |
| SCHEMBL21068092 | 0.70 | GPR3 (0.52) | GPR3KDM4EMAPTRAB9AALDH1A1 | |
| SCHEMBL16982228 | 0.68 | ALDH1A1 (0.41) | LIMK1KDM4EMAPTRAB9AALDH1A1 | |
| SCHEMBL14629288 | 0.68 | GPR3 (0.43) | GPR3LIMK1CDK5CDK5R1KDM4E | |
| SCHEMBL15746023 | 0.68 | GPR3 (0.43) | GPR3LIMK1CDK5CDK5R1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015114102-A1 | SILYL SUBSTITUTED AZADIBENZOFURANS AND AZADIBENZOTHIOPHENES | BASF SE (DE) | 2015-08-06 | — | — | WO | disclosed |