Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 8/20 | 0.46 |
| ▸ | ACHE | P22303 | 3/20 | 0.46 |
| ▸ | PTPRF | P10586 | 4/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 4/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.44 |
| ▸ | PDE9A | O76083 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16982822 | 1.00 | BCHE (0.46) | BCHEACHEPTPRFPTPN2PTPN1 | |
| SCHEMBL16949984 | 1.00 | BCHE (0.46) | BCHEACHEPTPRFPTPN2PTPN1 | |
| SCHEMBL16207692 | 0.92 | BCHE (0.47) | BCHEACHEPTPRFPTPN2PTPN1 | |
| SCHEMBL17583803 | 0.92 | BCHE (0.47) | BCHEACHEPTPRFPTPN2PTPN1 | |
| SCHEMBL17583806 | 0.92 | BCHE (0.47) | BCHEACHEPTPRFPTPN2PTPN1 | |
| SCHEMBL20371134 | 0.82 | GAA (0.45) | — | |
| SCHEMBL3839548 | 0.81 | GAA (0.43) | — | |
| SCHEMBL5964225 | 0.81 | GAA (0.43) | — | |
| SCHEMBL15709627 | 0.80 | BCHE (0.50) | BCHEACHEPTPRFPTPN2PTPN1 | |
| SCHEMBL20371135 | 0.79 | HDAC6 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015116502-A1 | DETECTION AND TREATMENT OF GNAQ MUTANT UVEAL MELANOMA CELLS WITH GOLD NANOPARTICLES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-08-06 | — | — | WO | disclosed |