Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | HTR7 | P34969 | 2/20 | 0.38 |
| ▸ | HTR6 | P50406 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.38 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20371134 | 0.90 | GAA (0.45) | HDAC6GAAKMT2AALDH1A1HTR1A | |
| SCHEMBL3839548 | 0.89 | GAA (0.43) | HDAC6GAAKMT2AALDH1A1CYP3A4 | |
| SCHEMBL5964225 | 0.89 | GAA (0.43) | HDAC6GAAKMT2AALDH1A1CYP3A4 | |
| SCHEMBL18349843 | 0.84 | HDAC1 (0.45) | HDAC6GAAKMT2AALDH1A1 | |
| SCHEMBL19709614 | 0.82 | HDAC6 (0.42) | HDAC6GAAKMT2AALDH1A1 | |
| SCHEMBL27240993 | 0.81 | SLC6A9 (0.41) | KMT2AALDH1A1 | |
| SCHEMBL27240989 | 0.81 | SLC6A9 (0.41) | KMT2AALDH1A1 | |
| SCHEMBL4447235 | 0.80 | KMT2A (0.52) | HDAC6KMT2AHTR1ADRD2HTR7 | |
| SCHEMBL16949984 | 0.79 | BCHE (0.46) | — | |
| SCHEMBL16982718 | 0.79 | BCHE (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180193471-A1 | ß2GPI GENE EXPRESSION-SUPPRESSING NUCLEIC ACID CONJUGATE | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2018-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180193471-A1 | ß2GPI GENE EXPRESSION-SUPPRESSING NUCLEIC ACID CONJUGATE | GALNT2, ST6GAL1, SLC17A5 | HDAC6 2964/4885GAA 359/4885KMT2A 2553/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.