Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 3/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | HTR7 | P34969 | 2/20 | 0.39 |
| ▸ | HTR6 | P50406 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5964225 | 1.00 | GAA (0.43) | GAAKMT2AALDH1A1KIF11KCNH2 | |
| SCHEMBL20371134 | 0.92 | GAA (0.45) | GAAKMT2AALDH1A1HDAC1HDAC6 | |
| SCHEMBL20371135 | 0.89 | HDAC6 (0.43) | GAAKMT2AALDH1A1HDAC6HTR1A | |
| SCHEMBL18349843 | 0.85 | HDAC1 (0.45) | GAAKMT2AALDH1A1HDAC1HDAC6 | |
| SCHEMBL19519943 | 0.85 | GAA (0.46) | GAAKMT2AALDH1A1KIF11KCNH2 | |
| SCHEMBL8842993 | 0.83 | MMP2 (0.46) | KMT2AALDH1A1KIF11KCNH2HDAC1 | |
| SCHEMBL19709614 | 0.83 | HDAC6 (0.42) | GAAKMT2AALDH1A1HDAC1HDAC6 | |
| SCHEMBL16949984 | 0.81 | BCHE (0.46) | — | |
| SCHEMBL16982718 | 0.81 | BCHE (0.46) | — | |
| SCHEMBL16982822 | 0.81 | BCHE (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2036897-B1 | Stable rhodamine labeling reagent | ROCHE DIAGNOSTICS GMBH (DE) | 2017-10-18 | — | — | EP | disclosed |
| EP-2036897-A1 | Stable rhodamine labeling reagent | Roche Diagnostics GmbH (DE) | 2009-03-18 | — | — | EP | disclosed |
| EP-2036897-A1 | Stable rhodamine labeling reagent | Roche Diagnostics GmbH (DE) | 2009-03-18 | — | — | EP | disclosed |