SCHEMBL16983239

SCHEMBL16983239

CCC[C@@H]1CCCN1C(=O)OCc1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PREP P48147 3/20 0.55
ACE2 Q9BYF1 3/20 0.54
TSHR P16473 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
KDM4E B2RXH2 1/20 0.53
LMNA P02545 1/20 0.53
PRCP P42785 1/20 0.53
NPSR1 Q6W5P4 1/20 0.52
TMEM97 Q5BJF2 1/20 0.52
SIGMAR1 Q99720 1/20 0.52
GFER P55789 1/20 0.50
NPC1 O15118 1/20 0.50
RAB9A P51151 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
CTRB1 P17538 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14646665 0.96 TMEM97 (0.56) PREPACE2TSHRL3MBTL1KDM4E
SCHEMBL19621551 0.96 TMEM97 (0.56) PREPACE2TSHRL3MBTL1KDM4E
SCHEMBL809534 0.90 PREP (0.57) PREPACE2TSHRL3MBTL1KDM4E
SCHEMBL16414618 0.88 PREP (0.54) PREPACE2TSHRL3MBTL1KDM4E
SCHEMBL9092052 0.87 PREP (0.53) PREPACE2TSHRL3MBTL1KDM4E
SCHEMBL29599061 0.87 PREP (0.53) PREPACE2TSHRL3MBTL1KDM4E
SCHEMBL18506025 0.87 PREP (0.50) PREPACE2TSHRL3MBTL1KDM4E
SCHEMBL3354292 0.86 PREP (0.54) PREPACE2NPSR1TMEM97SIGMAR1
SCHEMBL22158059 0.86 PREP (0.54) PREPACE2TSHRL3MBTL1KDM4E
SCHEMBL13060873 0.86 PREP (0.54) PREPACE2TSHRL3MBTL1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150218192-A1 Polysilylated Organosilane Compounds CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) 2015-08-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150218192-A1 Polysilylated Organosilane Compounds ALG8, UGT1A9, SI PREP 2037/4885ACE2 2760/4885TSHR 4451/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.