Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 19/20 | 0.52 |
| ▸ | CA1 | P00915 | 18/20 | 0.52 |
| ▸ | CA9 | Q16790 | 14/20 | 0.52 |
| ▸ | CA4 | P22748 | 11/20 | 0.52 |
| ▸ | CA12 | O43570 | 8/20 | 0.52 |
| ▸ | CA3 | P07451 | 8/20 | 0.52 |
| ▸ | CA6 | P23280 | 8/20 | 0.52 |
| ▸ | CA5A | P35218 | 8/20 | 0.52 |
| ▸ | CA7 | P43166 | 8/20 | 0.52 |
| ▸ | CA13 | Q8N1Q1 | 8/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 8/20 | 0.52 |
| ▸ | CA5B | Q9Y2D0 | 8/20 | 0.52 |
| ▸ | ALB | P02768 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19841188 | 0.84 | CA2 (0.54) | CA2CA1CA9CA4CA12 | |
| SCHEMBL26258159 | 0.84 | CA9 (0.47) | CA2CA1CA9CA4CA12 | |
| SCHEMBL18475438 | 0.84 | CA2 (0.55) | CA2CA1CA9CA4CA12 | |
| SCHEMBL16983571 | 0.83 | CA9 (0.53) | CA2CA1CA9CA4CA12 | |
| SCHEMBL16983521 | 0.83 | FOLH1 (0.52) | — | |
| SCHEMBL20629564 | 0.83 | FOLH1 (0.52) | — | |
| SCHEMBL23894081 | 0.83 | CA2 (0.56) | CA2CA1CA9CA4CA12 | |
| SCHEMBL18475601 | 0.82 | CA9 (0.49) | CA2CA1CA9CA4CA12 | |
| SCHEMBL23900418 | 0.81 | CA2 (0.60) | CA2CA1CA9CA4CA12 | |
| SCHEMBL18476511 | 0.81 | CA9 (0.43) | CA2CA1CA9CA4CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3424537-B1 | SMALL MOLECULE DRUG CONJUGATES | EIDGENOESSICHE TECHNISCHE HOCHSCHULE ZUERICH (CH) | 2021-01-13 | — | — | EP | disclosed |
| EP-3424537-A1 | SMALL MOLECULE DRUG CONJUGATES | Eidgenössiche Technische Hochschule Zürich (CH) | 2019-01-09 | — | — | EP | disclosed |
| WO-2015114171-A1 | SMALL MOLECULE DRUG CONJUGATES | EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZURICH (CH) | 2015-08-06 | — | — | WO | disclosed |