Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 20/20 | 0.56 |
| ▸ | CA1 | P00915 | 19/20 | 0.56 |
| ▸ | CA9 | Q16790 | 17/20 | 0.56 |
| ▸ | CA4 | P22748 | 15/20 | 0.56 |
| ▸ | CA12 | O43570 | 12/20 | 0.56 |
| ▸ | CA3 | P07451 | 12/20 | 0.56 |
| ▸ | CA6 | P23280 | 12/20 | 0.56 |
| ▸ | CA5A | P35218 | 12/20 | 0.56 |
| ▸ | CA7 | P43166 | 12/20 | 0.56 |
| ▸ | CA13 | Q8N1Q1 | 12/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 12/20 | 0.56 |
| ▸ | CA5B | Q9Y2D0 | 12/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23900418 | 0.93 | CA2 (0.60) | CA2CA1CA9CA4CA12 | |
| SCHEMBL23900244 | 0.92 | CA2 (0.52) | CA2CA1CA9CA4CA12 | |
| SCHEMBL18475438 | 0.92 | CA2 (0.55) | CA2CA1CA9CA4CA12 | |
| SCHEMBL19841188 | 0.91 | CA2 (0.54) | CA2CA1CA9CA4CA12 | |
| SCHEMBL18476489 | 0.89 | CA2 (0.59) | CA2CA1CA9CA4CA12 | |
| SCHEMBL20629617 | 0.85 | CA2 (0.59) | CA2CA1CA9CA4CA12 | |
| SCHEMBL18470085 | 0.85 | CA2 (0.54) | CA2CA1CA9CA4CA12 | |
| SCHEMBL24837486 | 0.83 | CA2 (0.46) | CA2CA1CA9CA4CA12 | |
| SCHEMBL16983568 | 0.83 | CA2 (0.52) | CA2CA1CA9CA4CA12 | |
| SCHEMBL22118542 | 0.81 | CA1 (0.80) | CA2CA1CA9CA4CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3888691-A1 | CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LIKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS | Hangzhou Dac Biotech Co., Ltd. (CN) | 2021-10-06 | — | — | EP | disclosed |