⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL321670 | 1.00 | — | — | |
| SCHEMBL1698570 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL3538913 | 0.98 | ALDH1A1 (0.51) | — | |
| Water SCHEMBL28237304 | 0.98 | ALDH1A1 (0.51) | — | |
| Methyl Alcohol SCHEMBL28090165 | 0.94 | ALDH1A1 (0.49) | — | |
| Methylene Chloride SCHEMBL7294170 | 0.94 | ALDH1A1 (0.49) | — | |
| SCHEMBL12081039 | 0.93 | ALDH1A1 (0.47) | — | |
| SCHEMBL12080775 | 0.93 | ALDH1A1 (0.47) | — | |
| SCHEMBL1967881 | 0.93 | ALDH1A1 (0.47) | — | |
| Alcohol SCHEMBL5062091 | 0.92 | ALDH1A1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114671864-B | Heteroaryl substituted pyridines and methods of use | 艾伯维公司 | 2025-04-08 | — | — | CN | disclosed |
| CN-114671864-A | Heteroaryl substituted pyridines and methods of use | 艾伯维公司 | 2022-06-28 | — | — | CN | disclosed |
| CN-109311864-B | Heteroaryl substituted pyridines and methods of use | 艾伯维公司 | 2022-05-10 | — | — | CN | disclosed |
| EP-3464282-B1 | HETEROARYL SUBSTITUTED PYRIDINES AND METHODS OF USE | ABBVIE OVERSEAS SARL (LU) | 2020-04-22 | — | — | EP | disclosed |
| US-10604515-B2 | Heteroaryl substituted pyridines and methods of use | ABBVIE S.Á.R.L. (LU) | 2020-03-31 | — | — | US | disclosed |
| US-20190055229-A1 | Heteroaryl Substituted Pyridines and Methods of Use | ABBVIE S.Á.R.L. (LU) | 2019-02-21 | — | — | US | disclosed |
| US-10138227-B2 | Heteroaryl substituted pyridines and methods of use | ABBVIE S.Á.R.L. (LU) | 2018-11-27 | — | — | US | disclosed |
| US-20170349576-A1 | HETEROARYL SUBSTITUTED PYRIDINES AND METHODS OF USE | ABBVIE S.Á.R.L. (LU) | 2017-12-07 | — | — | US | disclosed |
| US-8877778-B2 | Benzofurane compounds | HOFFMANN-LA ROCHE INC. (US) | 2014-11-04 | — | — | US | disclosed |
| EP-2582705-B1 | ANELLATED PYRIDINE COMPOUNDS AS DUAL MODULATORS OF THE 5-HT2A AND D3 RECEPTORS | HOFFMANN LA ROCHE (CH) | 2014-08-06 | — | — | EP | disclosed |
| CN-103402511-A | Novel benzodioxole piperidine compounds | HOFFMANN LA ROCHE | 2013-11-20 | — | — | CN | disclosed |
| US-8586579-B2 | Anellated pyridine compounds | HOFFMANN-LA ROCHE INC. (US) | 2013-11-19 | — | — | US | disclosed |
| EP-2651929-A1 | NOVEL BENZOFURANE COMPOUNDS | F.HOFFMANN-LA ROCHE AG (CH) | 2013-10-23 | — | — | EP | disclosed |
| EP-2582705-A1 | ANELLATED PYRIDINE COMPOUNDS AS DUAL MODULATORS OF THE 5-HT2A AND D3 RECEPTORS | F.HOFFMANN-LA ROCHE AG (CH) | 2013-04-24 | — | — | EP | disclosed |
| WO-2012117001-A1 | NOVEL BENZODIOXOLE PIPERIDINE COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2012-09-07 | — | — | WO | disclosed |
| US-20120225868-A1 | NOVEL BENZODIOXOLE PIPERIDINE COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2012-09-06 | — | — | US | disclosed |
| US-20120157449-A1 | BENZOFURANE COMPOUNDS | HOFFMANN-LA ROCHE INC. | 2012-06-21 | — | — | US | disclosed |
| WO-2012080149-A1 | NOVEL BENZOFURANE COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2012-06-21 | — | — | WO | disclosed |
| WO-2011161009-A1 | ANELLATED PYRIDINE COMPOUNDS AS DUAL MODULATORS OF THE 5-HT2A AND D3 RECEPTORS | F. HOFFMANN-LA ROCHE AG (CH) | 2011-12-29 | — | — | WO | disclosed |
| US-20110313151-A1 | ANELLATED PYRIDINE COMPOUNDS | HOFFMANN-LA ROCHE, INC. | 2011-12-22 | — | — | US | disclosed |