Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 11/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | AR | P10275 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | DRD1 | P21728 | 1/20 | 0.50 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3233268 | 0.84 | ESR1 (0.58) | ESR1CYP2C9TDP1LMNACYP1A2 | |
| SCHEMBL19333069 | 0.81 | ESR1 (0.33) | ESR1CYP2C9TDP1LMNACYP1A2 | |
| SCHEMBL69442 | 0.81 | ADRB2 (0.38) | CYP2C9LMNACYP3A4ADRA1AOPRM1 | |
| SCHEMBL27679481 | 0.80 | LMNA (0.43) | TDP1LMNACHRM2CHRM1ADRA1A | |
| SCHEMBL18297776 | 0.80 | ESR1 (0.54) | ESR1CYP2C9TDP1LMNACYP1A2 | |
| SCHEMBL12678056 | 0.80 | ESR1 (0.54) | ESR1CYP2C9TDP1LMNACYP1A2 | |
| SCHEMBL13197469 | 0.79 | ESR1 (0.59) | ESR1CYP2C9TDP1LMNACYP1A2 | |
| SCHEMBL12995870 | 0.77 | ESR1 (0.61) | ESR1CYP2C9TDP1LMNACYP1A2 | |
| SCHEMBL18782791 | 0.77 | ESR1 (0.50) | ESR1CYP2C9TDP1LMNACYP1A2 | |
| SCHEMBL19333062 | 0.76 | IDO1 (0.33) | ESR1LMNACYP3A4ESR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3819332-B1 | PROCESS FOR PRODUCING RIGID POLYURETHANE FOAMS | BASF SE (DE) | 2022-07-06 | — | — | EP | disclosed |
| EP-3819332-A1 | PROCESS FOR PRODUCING RIGID POLYURETHANE FOAMS | BASF SE (DE) | 2021-05-12 | — | — | EP | disclosed |
| EP-3099654-B1 | SYNTHETIC METHOD | UNIV COURT UNIV ST ANDREWS (GB) | 2018-05-09 | — | — | EP | disclosed |
| US-9908826-B2 | Synthetic method | UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) | 2018-03-06 | — | — | US | disclosed |
| US-9908826-B2 | Synthetic method | UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) | 2018-03-06 | — | — | US | disclosed |
| US-20170174608-A1 | Synthetic Method | UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) | 2017-06-22 | — | — | US | disclosed |
| US-20170174608-A1 | Synthetic Method | UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) | 2017-06-22 | — | — | US | disclosed |
| WO-2015114323-A1 | SYNTHETIC METHOD | UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) | 2015-08-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170174608-A1 | Synthetic Method | SQLE, FDFT1, CYP51A1 | ESR1 1178/4885CYP2C9 293/4885TDP1 2350/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.