SCHEMBL16984634

SCHEMBL16984634

c1ccc(-c2ccc3c(c2)oc2c3ccc3c4ccccc4oc32)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 5/20 0.47
PLA2G4A P47712 5/20 0.47
ALOX5 P09917 2/20 0.47
AHR P35869 3/20 0.47
MMP12 P39900 1/20 0.47
MMP13 P45452 1/20 0.47
MEN1 O00255 3/20 0.46
MAPT P10636 3/20 0.46
KMT2A Q03164 3/20 0.46
HPGD P15428 2/20 0.46
KDM4E B2RXH2 1/20 0.46
ALDH1A1 P00352 1/20 0.46
DYRK1A Q13627 1/20 0.44
GABRP O00591 1/20 0.43
GABRD O14764 1/20 0.43
NPC1 O15118 1/20 0.43
CA12 O43570 1/20 0.43
TNKS O95271 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24090393 0.96 PLA2G2A (0.50) PLA2G2APLA2G4AALOX5AHRMMP12
SCHEMBL19108694 0.96 PLA2G2A (0.47) PLA2G2APLA2G4AALOX5AHRMMP12
SCHEMBL1637390 0.94 PRKDC (0.44) PLA2G2APLA2G4AALOX5AHRMMP12
SCHEMBL17932124 0.93 PLA2G2A (0.43) PLA2G2APLA2G4AALOX5AHRMMP12
SCHEMBL1637813 0.91 PLA2G2A (0.42) PLA2G2APLA2G4AALOX5MMP12MMP13
SCHEMBL1636398 0.91 PRKDC (0.42) PLA2G2APLA2G4AALOX5AHRMMP12
SCHEMBL19196024 0.91 MAPT (0.43) PLA2G2APLA2G4AALOX5AHRMMP12
SCHEMBL24663126 0.91 PLA2G2A (0.46) PLA2G2APLA2G4AALOX5AHRMMP12
SCHEMBL20462456 0.90 AHR (0.57) PLA2G2APLA2G4AAHRMMP12MMP13
SCHEMBL13564016 0.90 DYRK1A (0.47) PLA2G2APLA2G4AALOX5AHRMMP12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150221876-A1 ORGANIC THIN FILM TRANSISTOR, ORGANIC SEMICONDUCTOR THIN FILM, AND ORGANIC SEMICONDUCTOR MATERIAL FUJIFILM CORPORATION (JP) 2015-08-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150221876-A1 ORGANIC THIN FILM TRANSISTOR, ORGANIC SEMICONDUCTOR THIN FILM, AND ORGANIC SEMICONDUCTOR MATERIAL OR10J3, POF1B, SLC43A1 PLA2G2A 4345/4885PLA2G4A 4660/4885ALOX5 3375/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.