Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16969236 | 0.92 | DGAT1 (0.65) | DGAT1ACAT1 | |
| SCHEMBL16969172 | 0.92 | DGAT1 (0.57) | DGAT1ACAT1 | |
| SCHEMBL16969194 | 0.91 | DGAT1 (0.65) | DGAT1ACAT1 | |
| SCHEMBL15640094 | 0.90 | DGAT1 (0.51) | DGAT1ACAT1 | |
| SCHEMBL16985182 | 0.89 | DGAT1 (0.62) | DGAT1ACAT1 | |
| SCHEMBL16969286 | 0.88 | DGAT1 (0.70) | DGAT1ACAT1 | |
| SCHEMBL3545569 | 0.84 | DGAT1 (0.60) | DGAT1ACAT1 | |
| SCHEMBL15638574 | 0.83 | DGAT1 (0.63) | DGAT1ACAT1 | |
| SCHEMBL3541638 | 0.83 | DGAT1 (0.61) | DGAT1ACAT1 | |
| SCHEMBL3538090 | 0.82 | DGAT1 (0.59) | DGAT1ACAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9550793-B2 | Spirocyclic compounds, compositions and medicinal applications thereof | ADVINUS THERAPEUTICS LIMITED (IN) | 2017-01-24 | — | — | US | disclosed |
| US-20150218187-A1 | SPIROCYCLIC COMPOUNDS, COMPOSITIONS AND MEDICINAL APPLICATIONS THEREOF | IMPETIS BIOSCIENCES LTD. (IN) | 2015-08-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150218187-A1 | SPIROCYCLIC COMPOUNDS, COMPOSITIONS AND MEDICINAL APPLICATIONS THEREOF | DGAT1, DGAT2, CPT1A | DGAT1 1/4885ACAT1 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.