Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | LATS1 | O95835 | 1/20 | 0.33 |
| ▸ | LATS2 | Q9NRM7 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16985336 | 0.85 | MAPT (0.35) | CYP2A13CNR2KDM4EPOLBGAA | |
| SCHEMBL16975423 | 0.80 | POLB (0.42) | KDM4EPOLBGAALMNANPC1 | |
| SCHEMBL16985325 | 0.73 | SMN1; SMN2 (0.35) | CYP2A13CNR2GAALATS1LATS2 | |
| SCHEMBL21266801 | 0.71 | NPC1 (0.41) | CYP2A13CNR2POLBCNR1LMNA | |
| SCHEMBL22726586 | 0.69 | SIGMAR1 (0.36) | CYP2A13CNR2GAALMNALATS1 | |
| SCHEMBL16975576 | 0.69 | MAP4K4 (0.34) | CNR2KDM4EGAALATS1LATS2 | |
| SCHEMBL16975309 | 0.66 | GAA (0.32) | GAALATS1LATS2SMN1; SMN2ALOX15 | |
| SCHEMBL17076668 | 0.65 | SMN1; SMN2 (0.33) | CYP2A13CNR2POLBGAASMN1; SMN2 | |
| SCHEMBL12221 | 0.65 | MEN1 (0.47) | POLBGAALMNANPC1RAB9A | |
| SCHEMBL16975469 | 0.64 | ALDH1A1 (0.43) | POLBLMNANPC1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015113452-A1 | COMPOUNDS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2015-08-06 | — | — | WO | disclosed |