Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 2/20 | 0.55 |
| ▸ | CFTR | P13569 | 1/20 | 0.55 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10013900 | 0.89 | ABCB1 (0.59) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL14350757 | 0.87 | ABCB1 (0.61) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL20111367 | 0.83 | ABCB1 (0.47) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL13966918 | 0.81 | ABCB1 (0.61) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL4572003 | 0.81 | SMN1; SMN2 (0.55) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL12192025 | 0.81 | ABCB1 (0.50) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL13179036 | 0.80 | ABCB1 (0.56) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL14071809 | 0.80 | USP2 (0.59) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL16232679 | 0.80 | ABCB1 (0.58) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL15006531 | 0.80 | ABCB1 (0.74) | ABCB1USP2CFTRPAX8ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9841426-B2 | Intracellular organelle peptide targeted enzyme substrates | MARKER GENE TECHNOLOGIES, INC (US) | 2017-12-12 | — | — | US | disclosed |
| US-20150219654-A1 | INTRACELLULAR ORGANELLE PEPTIDE TARGETED ENZYME SUBSTRATES | MARKER GENE TECHNOLOGIES, INC. | 2015-08-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150219654-A1 | INTRACELLULAR ORGANELLE PEPTIDE TARGETED ENZYME SUBSTRATES | GLG1, GBA3, MIA3 | ABCB1 3906/4885USP2 1294/4885CFTR 4067/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.