Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.59 |
| ▸ | USP2 | O75604 | 2/20 | 0.57 |
| ▸ | CFTR | P13569 | 1/20 | 0.57 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.57 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 4/20 | 0.42 |
| ▸ | CA9 | Q16790 | 4/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | DNASE1L3 | Q13609 | 1/20 | 0.40 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15006531 | 0.90 | ABCB1 (0.74) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL14350757 | 0.90 | ABCB1 (0.61) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL16985958 | 0.89 | ABCB1 (0.56) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL13966918 | 0.84 | ABCB1 (0.61) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL4572003 | 0.83 | SMN1; SMN2 (0.55) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL12192025 | 0.83 | ABCB1 (0.50) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL16232679 | 0.82 | ABCB1 (0.58) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL458205 | 0.82 | ABCB1 (0.77) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL13848619 | 0.81 | ABCB1 (0.58) | ABCB1USP2CFTRPAX8ATM | |
| Hydrochloric Acid SCHEMBL5606345 | 0.81 | USP2 (0.76) | ABCB1USP2CFTRPAX8ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8461358-B2 | Fluorescent probe for measuring protease | THE UNIVERSITY OF TOKYO (JP) | 2013-06-11 | — | — | US | disclosed |
| US-20120052518-A1 | FLUORESCENT PROBE FOR MEASURING PROTEASE | THE UNIVERSITY OF TOKYO (JP) | 2012-03-01 | — | — | US | disclosed |
| US-20120052518-A1 | FLUORESCENT PROBE FOR MEASURING PROTEASE | THE UNIVERSITY OF TOKYO (JP) | 2012-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120052518-A1 | FLUORESCENT PROBE FOR MEASURING PROTEASE | CTRL, PRSS3, PRSS1 | ABCB1 2822/4885USP2 733/4885CFTR 704/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.