Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.74 |
| ▸ | ATM | Q13315 | 2/20 | 0.71 |
| ▸ | USP2 | O75604 | 1/20 | 0.71 |
| ▸ | CFTR | P13569 | 1/20 | 0.71 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.71 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12285238 | 0.90 | ABCB1 (0.76) | ABCB1ATMUSP2CFTRPAX8 | |
| SCHEMBL10013900 | 0.90 | ABCB1 (0.59) | ABCB1ATMUSP2CFTRPAX8 | |
| SCHEMBL13881098 | 0.88 | ABCB1 (0.74) | ABCB1ATMUSP2CFTRPAX8 | |
| SCHEMBL12173205 | 0.87 | ABCB1 (0.72) | ABCB1ATMUSP2CFTRPAX8 | |
| SCHEMBL20216438 | 0.87 | ABCB1 (0.71) | ABCB1ATMUSP2CFTRPAX8 | |
| SCHEMBL20041379 | 0.87 | ABCB1 (0.71) | ABCB1ATMUSP2CFTRPAX8 | |
| SCHEMBL10167878 | 0.86 | ABCB1 (0.79) | ABCB1ATMUSP2CFTRPAX8 | |
| SCHEMBL16024743 | 0.86 | ABCB1 (0.79) | ABCB1ATMUSP2CFTRPAX8 | |
| SCHEMBL20216437 | 0.86 | ABCB1 (0.70) | ABCB1ATMUSP2CFTRPAX8 | |
| SCHEMBL268381 | 0.85 | ABCB1 (1.00) | ABCB1ATMUSP2CFTRPAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8461358-B2 | Fluorescent probe for measuring protease | THE UNIVERSITY OF TOKYO (JP) | 2013-06-11 | — | — | US | disclosed |