Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.97 |
| ▸ | DRD3 | P35462 | 6/20 | 0.72 |
| ▸ | HTR1A | P08908 | 4/20 | 0.72 |
| ▸ | MEN1 | O00255 | 1/20 | 0.72 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.72 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.72 |
| ▸ | DRD1 | P21728 | 1/20 | 0.72 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.72 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.72 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.72 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.72 |
| ▸ | DRD2 | P14416 | 8/20 | 0.66 |
| ▸ | DRD4 | P21917 | 5/20 | 0.66 |
| ▸ | HTR2A | P28223 | 3/20 | 0.66 |
| ▸ | HRH1 | P35367 | 3/20 | 0.66 |
| ▸ | HTR2C | P28335 | 2/20 | 0.66 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL16986196 | 0.98 | TSHR (1.00) | TSHRDRD3HTR1AMEN1CHRM2 | |
| SCHEMBL16986160 | 0.90 | TSHR (0.79) | TSHRDRD3HTR1AMEN1CHRM2 | |
| Hydrochloric Acid SCHEMBL16986146 | 0.88 | TSHR (0.82) | TSHRDRD3HTR1AMEN1CHRM2 | |
| SCHEMBL4496558 | 0.88 | TSHR (0.76) | TSHRDRD3HTR1AMEN1CHRM2 | |
| Primaperone SCHEMBL310299 | 0.86 | TSHR (0.74) | TSHRDRD3HTR1AMEN1CHRM2 | |
| SCHEMBL11832182 | 0.85 | DRD2 (0.88) | TSHRDRD3HTR1AMEN1CHRM2 | |
| SCHEMBL28432024 | 0.85 | TSHR (0.72) | TSHRDRD3HTR1AMEN1CHRM2 | |
| Primaperone SCHEMBL364809 | 0.85 | TSHR (0.76) | TSHRDRD3HTR1AMEN1CHRM2 | |
| Melperone SCHEMBL146287 | 0.84 | KMT2A (1.00) | TSHRDRD3HTR1AMEN1CHRM2 | |
| SCHEMBL7755956 | 0.84 | TSHR (0.70) | TSHRDRD3HTR1AMEN1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150266864-A1 | HETEROAROMATIC COMPOUNDS, METHOD FOR PREPARING THE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, USES AND METHOD FOR TREATING ACUTE AND CHRONIC PAIN | CRISTÁLIA PRODUTOS QUÍMICOS FARMACÊUTICOS LTDA (BR) | 2015-09-24 | — | — | US | disclosed |
| EP-2905278-A1 | HETEROAROMATIC COMPOUNDS, METHOD FOR PREPARING THE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, USES AND METHOD FOR TREATING ACUTE AND CHRONIC PAIN | Cristália Produtos Químicos Farmacêuticos LTDA. (BR) | 2015-08-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150266864-A1 | HETEROAROMATIC COMPOUNDS, METHOD FOR PREPARING THE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, USES AND METHOD FOR TREATING ACUTE AND CHRONIC PAIN | TRPV1, AP1G1, INA | TSHR 4678/4885DRD3 2293/4885HTR1A 670/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.