Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL959315 | 0.82 | RXFP1 (0.57) | PKMRECQLRXFP1KDM4EMEN1 | |
| SCHEMBL956847 | 0.77 | MAPT (0.53) | RECQLRXFP1KDM4EMEN1ALDH1A1 | |
| SCHEMBL955495 | 0.75 | LMNA (0.66) | KDM4EMEN1KMT2A | |
| SCHEMBL8220374 | 0.74 | KDM4E (0.62) | KDM4EMEN1KMT2A | |
| SCHEMBL954020 | 0.73 | KMT2A (0.52) | RECQLRXFP1KDM4EMEN1ALDH1A1 | |
| SCHEMBL6055037 | 0.71 | MEN1 (0.53) | KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL953001 | 0.71 | JAK2 (0.45) | PKMRECQLRXFP1KDM4EMEN1 | |
| SCHEMBL954639 | 0.71 | RAB9A (0.64) | RXFP1MEN1ALDH1A1KMT2A | |
| SCHEMBL8215155 | 0.70 | NPC1 (0.51) | PKMKDM4E | |
| SCHEMBL956108 | 0.70 | MEN1 (0.59) | MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1845973-B1 | PHARMACEUTICAL COMPOUNDS | ASTEX THERAPEUTICS LTD (GB) | 2015-08-12 | — | — | EP | disclosed |