Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16962751 | 1.00 | KMT2A (0.41) | KMT2AMEN1MAPK1GAARAB9A | |
| SCHEMBL16962752 | 1.00 | KMT2A (0.41) | KMT2AMEN1MAPK1GAARAB9A | |
| SCHEMBL27524337 | 0.81 | GAA (0.41) | KMT2AMEN1MAPK1GAARAB9A | |
| SCHEMBL11026593 | 0.78 | GAA (0.42) | MAPK1GAARAB9ANPC1HTT | |
| SCHEMBL11026594 | 0.78 | GAA (0.42) | MAPK1GAARAB9ANPC1HTT | |
| SCHEMBL6792348 | 0.76 | GAA (0.44) | KMT2AMEN1MAPK1GAARAB9A | |
| SCHEMBL31492998 | 0.74 | KMT2A (0.45) | KMT2AMEN1MAPK1RAB9ANPC1 | |
| SCHEMBL11929836 | 0.74 | KMT2A (0.45) | KMT2AMEN1MAPK1RAB9ANPC1 | |
| SCHEMBL18234088 | 0.72 | KDM4E (0.48) | KMT2AMAPK1ALDH1A1HSP90AA1KDM4E | |
| SCHEMBL16845587 | 0.72 | KDM4E (0.48) | KMT2AMAPK1ALDH1A1HSP90AA1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10104892-B2 | Herbicidally and fungicidally active 3-heteroaryl-isoxazoline-5-carboxamides and 3-heteroaryl-isoxazoline-5-thioamides | BAYER CROPSCIENCE AG (DE) | 2018-10-23 | — | — | US | disclosed |
| US-20150223461-A1 | HERBICIDALLY AND FUNGICIDALLY ACTIVE 3-HETEROARYL-ISOXAZOLINE-5-CARBOXAMIDES AND 3-HETEROARYL-ISOXAZOLINE-5-THIOAMIDES | BAYER CROPSCIENCE AG (DE) | 2015-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10104892-B2 | Herbicidally and fungicidally active 3-heteroaryl-isoxazoline-5-carboxamides and 3-heteroaryl-isoxazoline-5-thioamides | CYP4X1, PRDX3, CYP3A7 | KMT2A 1041/4885MEN1 4812/4885MAPK1 3952/4885 |
| US-20150223461-A1 | HERBICIDALLY AND FUNGICIDALLY ACTIVE 3-HETEROARYL-ISOXAZOLINE-5-CARBOXAMIDES AND 3-HETEROARYL-ISOXAZOLINE-5-THIOAMIDES | CBR3, CYP3A7, PRDX3 | KMT2A 1050/4885MEN1 4818/4885MAPK1 4006/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.