Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 3/20 | 0.52 |
| ▸ | CES2 | O00748 | 2/20 | 0.50 |
| ▸ | CES1 | P23141 | 2/20 | 0.50 |
| ▸ | MLYCD | O95822 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | ERN1 | O75460 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15631128 | 0.83 | ERN1 (0.49) | ANPEPMLYCDNPSR1HDAC1HDAC6 | |
| SCHEMBL4443226 | 0.83 | MLYCD (0.53) | MLYCDNPSR1ALDH1A1LMNACYP1A2 | |
| SCHEMBL13702129 | 0.82 | MLYCD (0.55) | CES2CES1MLYCDNPSR1ALDH1A1 | |
| SCHEMBL31079673 | 0.81 | MLYCD (0.54) | ANPEPCES2CES1MLYCDNPSR1 | |
| SCHEMBL13146304 | 0.81 | MLYCD (0.54) | ANPEPCES2CES1MLYCDNPSR1 | |
| SCHEMBL17732584 | 0.80 | ERN1 (0.47) | ANPEPMLYCDNPSR1HDAC1HDAC6 | |
| SCHEMBL23309675 | 0.78 | MLYCD (0.47) | MLYCDNPSR1ALDH1A1LMNACYP1A2 | |
| SCHEMBL3755988 | 0.78 | HDAC1 (0.67) | ANPEPMLYCDNPSR1HDAC1HDAC6 | |
| SCHEMBL20207014 | 0.78 | KDM4E (0.55) | MLYCDNPSR1ALDH1A1LMNAXDH | |
| SCHEMBL7981473 | 0.77 | CES2 (0.56) | ANPEPCES2CES1HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024028243-A1 | PYRAZOLO PESTICIDAL COMPOUNDS | BASF SE (DE) | 2024-02-08 | — | — | WO | disclosed |
| US-20200181077-A1 | CYCLOPROPYLAMINES AS LSD1 INHIBITORS | INCYTE CORPORATION (US) | 2020-06-11 | — | — | US | disclosed |
| US-20170158633-A1 | CYCLOPROPYLAMINES AS LSD1 INHIBITORS | INCYTE CORPORATION (US) | 2017-06-08 | — | — | US | disclosed |
| US-9527835-B2 | Cyclopropylamines as LSD1 inhibitors | INCYTE CORPORATION (US) | 2016-12-27 | — | — | US | disclosed |
| US-20150225375-A1 | CYCLOPROPYLAMINES AS LSD1 INHIBITORS | INCYTE CORPORATION (US) | 2015-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150225375-A1 | CYCLOPROPYLAMINES AS LSD1 INHIBITORS | KDM1B, KDM1A, KDM2A | ANPEP 3443/4885CES2 992/4885CES1 692/4885 |
| US-20200181077-A1 | CYCLOPROPYLAMINES AS LSD1 INHIBITORS | KDM1B, KDM1A, KDM2A | ANPEP 3443/4885CES2 992/4885CES1 692/4885 |
| US-20170158633-A1 | CYCLOPROPYLAMINES AS LSD1 INHIBITORS | KDM1B, KDM1A, KDM2A | ANPEP 3443/4885CES2 992/4885CES1 692/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.