Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR2 | Q16832 | 2/20 | 0.70 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | BRAF | P15056 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | CCR3 | P51677 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RAF1 | P04049 | 1/20 | 0.43 |
| ▸ | PYGL | P06737 | 2/20 | 0.43 |
| ▸ | PYGM | P11217 | 2/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15575225 | 0.92 | DDR2 (0.83) | DDR2P2RX3L3MBTL1ALDH1A1CYP1A2 | |
| SCHEMBL16990622 | 0.90 | DDR2 (0.84) | DDR2L3MBTL1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL16990665 | 0.89 | DDR2 (0.69) | DDR2P2RX3L3MBTL1ALDH1A1CYP1A2 | |
| SCHEMBL16990626 | 0.89 | DDR2 (0.60) | DDR2P2RX3L3MBTL1ALDH1A1KMT2A | |
| SCHEMBL16990668 | 0.89 | DDR2 (0.60) | DDR2P2RX3L3MBTL1ALDH1A1MAPT | |
| SCHEMBL16990638 | 0.88 | RAF1 (0.57) | DDR2L3MBTL1KMT2ABRAFKDR | |
| SCHEMBL15574835 | 0.87 | DDR2 (0.61) | DDR2L3MBTL1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL16990682 | 0.87 | RAF1 (0.58) | DDR2P2RX3L3MBTL1BRAFKDR | |
| SCHEMBL15573349 | 0.82 | DDR2 (0.59) | DDR2P2RX3L3MBTL1ALDH1A1MAPT | |
| SCHEMBL13603518 | 0.82 | DDR2 (1.00) | DDR2P2RX3L3MBTL1ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150225369-A1 | DDR2 INHIBITORS FOR THE TREATMENT OF OSTEOARTHRITIS | MERCK PATENT GMBH (DE) | 2015-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150225369-A1 | DDR2 INHIBITORS FOR THE TREATMENT OF OSTEOARTHRITIS | DDR2, DDR1, DDRGK1 | DDR2 1/4885P2RX3 540/4885L3MBTL1 3554/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.