Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR2 | Q16832 | 2/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | RAF1 | P04049 | 5/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.47 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15573349 | 0.93 | DDR2 (0.59) | DDR2L3MBTL1ALDH1A1RAF1MAPT | |
| SCHEMBL16990683 | 0.92 | L3MBTL1 (0.62) | DDR2L3MBTL1ALDH1A1RAF1MAPT | |
| SCHEMBL15574169 | 0.91 | DDR2 (0.82) | DDR2L3MBTL1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL16990622 | 0.90 | DDR2 (0.84) | DDR2L3MBTL1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL15575329 | 0.90 | KMT2A (0.60) | DDR2L3MBTL1ALDH1A1RAF1TP53 | |
| SCHEMBL16990616 | 0.89 | DDR2 (0.70) | DDR2L3MBTL1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL15574618 | 0.89 | DDR2 (0.55) | DDR2L3MBTL1ALDH1A1RAF1TP53 | |
| SCHEMBL16990688 | 0.89 | DDR2 (0.59) | DDR2CYP1A2CYP2C19TP53MAPT | |
| SCHEMBL16990591 | 0.88 | DDR2 (0.63) | DDR2L3MBTL1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL16990693 | 0.88 | HDAC1 (0.55) | DDR2L3MBTL1ALDH1A1RAF1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150225369-A1 | DDR2 INHIBITORS FOR THE TREATMENT OF OSTEOARTHRITIS | MERCK PATENT GMBH (DE) | 2015-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150225369-A1 | DDR2 INHIBITORS FOR THE TREATMENT OF OSTEOARTHRITIS | DDR2, DDR1, DDRGK1 | DDR2 1/4885L3MBTL1 3554/4885ALDH1A1 2098/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.