Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | PYGL | P06737 | 3/20 | 0.45 |
| ▸ | PYGM | P11217 | 3/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | DDR2 | Q16832 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MET | P08581 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | CSF1R | P07333 | 2/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | FLT4 | P35916 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13603524 | 0.91 | DDR2 (0.53) | ALDH1A1KMT2AKDM4EMEN1DDR2 | |
| SCHEMBL16990613 | 0.84 | GSK3B (0.48) | ALDH1A1KMT2AKDM4EMEN1PYGL | |
| SCHEMBL16990693 | 0.83 | HDAC1 (0.55) | ALDH1A1KMT2AKDM4EMEN1PYGL | |
| SCHEMBL15574571 | 0.82 | NAMPT (0.49) | KDM4ENPC1RAB9ACSF1R | |
| SCHEMBL15574560 | 0.80 | NPC1 (0.58) | KMT2AMEN1NPC1RAB9ACSF1R | |
| SCHEMBL16990683 | 0.80 | L3MBTL1 (0.62) | ALDH1A1KMT2APYGLPYGMDDR2 | |
| SCHEMBL15574905 | 0.80 | GCK (0.47) | PYGLPYGMNPC1RAB9AMET | |
| SCHEMBL15574737 | 0.79 | DDR2 (0.53) | ALDH1A1KMT2AKDM4EMEN1TRPV1 | |
| SCHEMBL4173358 | 0.79 | RAF1 (0.52) | KMT2AMEN1 | |
| SCHEMBL257963 | 0.79 | RAF1 (0.59) | KMT2AMEN1DDR2METGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150225369-A1 | DDR2 INHIBITORS FOR THE TREATMENT OF OSTEOARTHRITIS | MERCK PATENT GMBH (DE) | 2015-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150225369-A1 | DDR2 INHIBITORS FOR THE TREATMENT OF OSTEOARTHRITIS | DDR2, DDR1, DDRGK1 | ALDH1A1 2098/4885KMT2A 3848/4885KDM4E 4649/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.