⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28899896 | 0.77 | CA1 (0.30) | — | |
| SCHEMBL3392764 | 0.73 | — | — | |
| SCHEMBL27923820 | 0.72 | — | — | |
| SCHEMBL13606445 | 0.71 | F2 (0.34) | — | |
| SCHEMBL9418274 | 0.70 | — | — | |
| SCHEMBL16743129 | 0.69 | CA1 (0.50) | — | |
| SCHEMBL5165989 | 0.69 | CA1 (0.50) | — | |
| SCHEMBL1659675 | 0.67 | TRPM8 (0.48) | — | |
| SCHEMBL16411374 | 0.65 | MEN1 (0.36) | — | |
| SCHEMBL22631554 | 0.64 | LMNA (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3658109-B1 | COOLING AND FLAVOR BOOSTING COMPOSITIONS | FIRMENICH & CIE (CH) | 2022-12-07 | — | — | EP | claimed |
| EP-3081207-B1 | USE OF A LIPOSOME COMPOSITION | SYMRISE AG (DE) | 2022-09-21 | — | — | EP | claimed |
| CN-111032003-A | Cooling and flavor enhancing compositions | 弗门尼舍有限公司 | 2020-04-17 | — | — | CN | claimed |
| US-10392371-B2 | Compounds useful as modulators of TRPM8 | SENOMYX, INC. (US) | 2019-08-27 | — | — | US | claimed |
| US-20190099342-A1 | COOLING PRODUCT | SYMRISE AG (DE) | 2019-04-04 | — | — | US | claimed |
| WO-2016166038-A1 | WHITENING COMPOSITIONS | SYMRISE AG (DE) | 2016-10-20 | — | — | WO | claimed |
| EP-3081207-A1 | WHITENING COMPOSITIONS | Symrise AG (DE) | 2016-10-19 | — | — | EP | claimed |
| EP-4725476-A2 | COMPOSITIONS FOR REDUCING SALTY TASTE AND USES THEREOF | Firmenich SA (CH) | 2026-04-15 | — | — | EP | disclosed |
| EP-4096714-B1 | COMPOSITIONS FOR REDUCING SALTY TASTE AND USES THEREOF | FIRMENICH & CIE (CH) | 2026-01-28 | — | — | EP | disclosed |
| EP-4251122-B1 | COMPOSITIONS THAT ENHANCE THE COOLING EFFECT | FIRMENICH INCORPORATED (US) | 2025-03-12 | — | — | EP | disclosed |
| US-20250064063-A1 | ANTIMICROBIAL COMPOSITION HAVING ENCAPSULATED COLORANT | FIRMENICH SA (CH) | 2025-02-27 | — | — | US | disclosed |
| EP-3663366-B1 | USE OF PHYSIOLOGICAL COOLING INGREDIENTS AND AGENTS CONTAINING SUCH ACTIVE INGREDIENTS | SYMRISE AG (DE) | 2025-01-08 | — | — | EP | disclosed |
| US-20240307279-A1 | FAST DRYING PERFUME COMPOSITION | FIRMENICH SA (CH) | 2024-09-19 | — | — | US | disclosed |
| EP-2501761-A2 | USE OF PHYSIOLOGICAL COOLING ACTIVE INGREDIENTS, AND AGENTS CONTAINING SUCH ACTIVE INGREDIENTS | Symrise AG (DE) | 2012-09-26 | — | — | EP | disclosed |
| WO-2011061330-A9 | USE OF PHYSIOLOGICAL COOLING ACTIVE INGREDIENTS, AND AGENTS CONTAINING SUCH ACTIVE INGREDIENTS | SYMRISE AG (DE) | 2012-01-05 | — | — | WO | disclosed |
| US-20110305657-A1 | Cooling Mixtures with an enhanced cooling effect of 5-methyl-2-(propane-2-yl)cyclohexyl-N-ethyloxamate | SYMRISE AG (DE) | 2011-12-15 | — | — | US | disclosed |
| EP-2394703-A1 | Cooling mixture with reinforced cooling effect of 5-methyl-2-(propan-2-yl)cyclohexyl-N-ethyloxamate | Symrise AG (DE) | 2011-12-14 | — | — | EP | disclosed |
| US-20110145970-A1 | DETECTION AND USE OF LOW MOLECULAR-WEIGHT MODULATORS OF THE COLD-MENTHOL RECEPTOR TRPM8 | BASF SE (DE) | 2011-06-23 | — | — | US | disclosed |
| WO-2011061330-A2 | USE OF PHYSIOLOGICAL COOLING ACTIVE INGREDIENTS, AND AGENTS CONTAINING SUCH ACTIVE INGREDIENTS | SYMRISE AG (DE) | 2011-05-26 | — | — | WO | disclosed |
| WO-2010149798-A2 | USE OF POLYOLS FOR ENHANCING THE COOLING EFFECT OF A COOLING SUBSTANCE AND COOLING MIXTURES HAVING AN ENHANCED COOLING EFFECT | SYMRISE AG (DE) | 2010-12-29 | — | — | WO | disclosed |