SCHEMBL16992123

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL27373378	1.00	CHRM4 (0.50)	CHRM4POLBCHRM2ALDH1A1CYP3A4
	SCHEMBL27373106	0.84	SCD5 (0.42)	CHRM4POLBKMT2ASMN1; SMN2HRH3
	SCHEMBL20310714	0.83	CHRM4 (0.54)	CHRM4POLBCHRM2ALDH1A1CYP2C9
	SCHEMBL20310706	0.82	CHRM4 (0.57)	CHRM4CHRM2ALDH1A1MAPK1TP53
	SCHEMBL16992573	0.82	CHRM4 (0.54)	CHRM4CHRM2ALDH1A1MAPK1TSHR
	SCHEMBL27372454	0.82	ALDH1A1 (0.39)	ALDH1A1CYP2C19KMT2AMAPK1LMNA
	SCHEMBL17020250	0.81	CHRM4 (0.56)	CHRM4POLBCHRM2ALDH1A1CYP3A4
	SCHEMBL15618604	0.81	CHRM4 (0.50)	CHRM4POLBCHRM2ALDH1A1KMT2A
	SCHEMBL20310664	0.80	CHRM4 (0.57)	CHRM4POLBCHRM2ALDH1A1KMT2A
	SCHEMBL17001770	0.80	CHRM4 (0.54)	CHRM4POLBCHRM2ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.