SCHEMBL16992152

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20909015	0.86	IRAK4 (0.40)	GAAHSD17B10L3MBTL1HTTSMN1; SMN2
	SCHEMBL1662358	0.83	KDM4E (0.50)	ALDH1A1KDM4EHPGDNPSR1HSD17B10
	SCHEMBL16992445	0.81	CHRM4 (0.57)	ALDH1A1KDM4EHPGDNPSR1GAA
	SCHEMBL1664728	0.80	HTR2B (0.40)	ALDH1A1HPGDNPSR1L3MBTL1HTT
	SCHEMBL16992488	0.79	NOS2 (0.46)	ALDH1A1KDM4EHPGDNPSR1GAA
	SCHEMBL19924942	0.77	POLB (0.64)	HSD17B10SMN1; SMN2MAPT
	SCHEMBL4485955	0.73	ALDH1A1 (0.46)	ALDH1A1KDM4EHPGDNPSR1GAA
	SCHEMBL17001700	0.73	HTR2B (0.53)	ALDH1A1KDM4EHPGDNPSR1GAA
	SCHEMBL8434541	0.72	GAA (0.62)	ALDH1A1KDM4EGAATSHRL3MBTL1
	SCHEMBL3629079	0.70	GAA (0.70)	ALDH1A1GAATSHRL3MBTL1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.