SCHEMBL1699233

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10272096	0.85	CYP3A4 (0.49)	CYP3A4CCR1CCR8PKM
	SCHEMBL15099580	0.84	CYP3A4 (0.54)	CYP3A4SMN1; SMN2CREBBPMAPK14
	SCHEMBL1701636	0.84	CYP3A4 (0.54)	CYP3A4CCR1CCR8CREBBPMAPK14
	SCHEMBL1699718	0.83	CYP3A4 (0.62)	CYP3A4CCR1CCR8CREBBPMAPK14
	SCHEMBL1699715	0.83	CYP3A4 (0.62)	CYP3A4CCR1CCR8CREBBPMAPK14
	SCHEMBL10272189	0.80	CYP3A4 (0.56)	CYP3A4MAPTMAPK1L3MBTL1RAB9A
	SCHEMBL1699255	0.80	CYP3A4 (0.62)	CYP3A4MAPK14
	SCHEMBL1699611	0.79	CYP3A4 (0.51)	CYP3A4PDE4DPKM
	SCHEMBL16381382	0.79	CYP3A4 (0.61)	CYP3A4MAPK14
	SCHEMBL15165108	0.79	CYP3A4 (0.70)	CYP3A4MAPK14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.