Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.42 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16993675 | 1.00 | LMNA (0.44) | LMNAALDH1A1RECQLNPFFR1NPFFR2 | |
| Hydrochloric Acid SCHEMBL6510408 | 0.99 | LMNA (0.43) | LMNAALDH1A1RECQLNPFFR1NPFFR2 | |
| Hydrochloric Acid SCHEMBL6510411 | 0.99 | LMNA (0.43) | LMNAALDH1A1RECQLNPFFR1NPFFR2 | |
| SCHEMBL17044426 | 0.90 | LMNA (0.46) | LMNAALDH1A1RECQLNPFFR1NPFFR2 | |
| SCHEMBL17044425 | 0.90 | LMNA (0.46) | LMNAALDH1A1RECQLNPFFR1NPFFR2 | |
| Hydrochloric Acid SCHEMBL5703240 | 0.89 | LMNA (0.44) | LMNAALDH1A1RECQLNPFFR1NPFFR2 | |
| Hydrochloric Acid SCHEMBL5703242 | 0.89 | LMNA (0.44) | LMNAALDH1A1RECQLNPFFR1NPFFR2 | |
| SCHEMBL17044396 | 0.84 | NPFFR2 (0.60) | LMNAALDH1A1RECQLNPFFR1NPFFR2 | |
| SCHEMBL17044397 | 0.84 | NPFFR2 (0.60) | LMNAALDH1A1RECQLNPFFR1NPFFR2 | |
| Hydrochloric Acid SCHEMBL5703225 | 0.83 | NPFFR2 (0.61) | LMNAALDH1A1RECQLNPFFR1NPFFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150246140-A1 | COMPOSITIONS AND METHODS FOR MODULATING SLEEP AND WAKEFULNESS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2015-09-03 | — | — | US | disclosed |
| WO-2015120446-A1 | COMPOSITIONS AND METHODS FOR MODULATING SLEEP AND WAKEFULENESS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2015-08-13 | — | — | WO | disclosed |
| US-20150065485-A1 | SUBSTITUTED POLYCYCLIC CARBAMOYLPYRIDONE DERIVATIVE | SHIONOGI & CO (JP) | 2015-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150065485-A1 | SUBSTITUTED POLYCYCLIC CARBAMOYLPYRIDONE DERIVATIVE | CNBP, ZC3HAV1, DPP4 | LMNA 1705/4885ALDH1A1 1813/4885RECQL 1680/4885 |
| US-20150246140-A1 | COMPOSITIONS AND METHODS FOR MODULATING SLEEP AND WAKEFULNESS | HCRTR2, HCRTR1, NPSR1 | LMNA 866/4885ALDH1A1 4570/4885RECQL 3470/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.