Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.81 |
| ▸ | LMNA | P02545 | 1/20 | 0.81 |
| ▸ | PKM | P14618 | 4/20 | 0.69 |
| ▸ | HTT | P42858 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.69 |
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10130742 | 0.90 | GAA (1.00) | GAALMNAPKMHTTALDH1A1 | |
| SCHEMBL3971438 | 0.87 | PKM (0.88) | GAALMNAPKMHTTALDH1A1 | |
| SCHEMBL699639 | 0.87 | PKM (0.88) | GAALMNAPKMHTTALDH1A1 | |
| SCHEMBL3303527 | 0.87 | PKM (0.88) | GAALMNAPKMHTTALDH1A1 | |
| SCHEMBL4537086 | 0.87 | PKM (0.88) | GAALMNAPKMHTTALDH1A1 | |
| SCHEMBL8200466 | 0.87 | PKM (0.88) | GAALMNAPKMHTTALDH1A1 | |
| SCHEMBL10724066 | 0.87 | PKM (0.88) | GAALMNAPKMHTTALDH1A1 | |
| SCHEMBL8203532 | 0.87 | PKM (0.88) | GAALMNAPKMHTTALDH1A1 | |
| SCHEMBL565301 | 0.87 | PKM (0.88) | GAALMNAPKMHTTALDH1A1 | |
| SCHEMBL3110096 | 0.82 | PKM (1.00) | GAALMNAPKMHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2590952-A1 | 1,2-BIS-(4,7-DIMETHYL-1,4,7-TRIAZACYCLONON-1-YL)-ETHANE AND INTERMEDIATE THEREOF | Catexel Limited (GB) | 2013-05-15 | — | — | EP | disclosed |
| WO-2012003712-A1 | 1,2-BIS-(4,7-DIMETHYL-1,4,7-TRIAZACYCLONON-1-YL)-ETHANE AND INTERMEDIATE THEREOF | UNILEVER PLC (GB) | 2012-01-12 | — | — | WO | disclosed |