Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.31 |
| ▸ | USP2 | O75604 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16995178 | 0.86 | POLB (0.34) | MEN1KMT2ASYK | |
| SCHEMBL16995177 | 0.84 | KCNH3 (0.33) | CYP1A2USP2TSHRMEN1KMT2A | |
| SCHEMBL16986371 | 0.71 | SCN9A (0.31) | SCN9A | |
| SCHEMBL17001192 | 0.71 | KMT2A (0.39) | TSHRKMT2AHPGDMAPTSYK | |
| SCHEMBL16986319 | 0.70 | KDM4C (0.37) | MEN1KMT2AMAPT | |
| SCHEMBL16986342 | 0.69 | KMT2A (0.36) | TSHRKMT2A | |
| SCHEMBL16986356 | 0.67 | KMT2A (0.38) | TSHRKMT2AALDH1A1SYK | |
| SCHEMBL16986367 | 0.66 | GSK3B (0.38) | ALDH1A1HPGD | |
| SCHEMBL16986364 | 0.65 | POLB (0.36) | TSHRMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL17001193 | 0.63 | KCNH3 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015118110-A1 | PYRIDO[2,3-D]PYRIMIDINE-7(8H)-ONE DERIVATIVES FOR THE TREATMENT OF HEPATITIS C | INSTITUT QUÍMIC DE SARRIÁ, CETS FUNDACIÓ PRIVADA (ES) | 2015-08-13 | — | — | WO | disclosed |
| EP-2905024-A1 | Pyrido[2,3-d]pyrimidine-7(8H)-one derivatives for the treatment of infections caused by Flaviviridae | Institut Quimic De Sarriá Cets, Fundació Privada (ES) | 2015-08-12 | — | — | EP | disclosed |