Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16986342 | 0.85 | KMT2A (0.36) | KMT2ASMN1; SMN2TSHRCASP3SENP8 | |
| SCHEMBL16995178 | 0.84 | POLB (0.34) | KMT2ASYKSIRT2NPC1RAB9A | |
| SCHEMBL16986358 | 0.79 | TP53 (0.36) | TP53MAPT | |
| SCHEMBL16986356 | 0.75 | KMT2A (0.38) | KMT2ASYKSMN1; SMN2TSHRCASP3 | |
| SCHEMBL16986309 | 0.74 | KCNJ5 (0.34) | TP53TSHR | |
| SCHEMBL16986348 | 0.72 | CDK1 (0.35) | TP53NPC1 | |
| SCHEMBL16986347 | 0.71 | KMT2A (0.36) | KMT2ASMN1; SMN2TSHRCASP3SENP8 | |
| SCHEMBL16995175 | 0.71 | SCN9A (0.32) | KMT2ASYKTSHRMAPTHPGD | |
| SCHEMBL16995177 | 0.70 | KCNH3 (0.33) | KMT2ATSHRNPC1HPGDRAB9A | |
| SCHEMBL16310227 | 0.67 | TP53 (0.38) | TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015118110-A1 | PYRIDO[2,3-D]PYRIMIDINE-7(8H)-ONE DERIVATIVES FOR THE TREATMENT OF HEPATITIS C | INSTITUT QUÍMIC DE SARRIÁ, CETS FUNDACIÓ PRIVADA (ES) | 2015-08-13 | — | — | WO | disclosed |