Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | DRD4 | P21917 | 10/20 | 0.48 |
| ▸ | DRD2 | P14416 | 8/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MC4R | P32245 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | CDK14 | O94921 | 2/20 | 0.44 |
| ▸ | CCNY | Q8ND76 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8219241 | 0.94 | L3MBTL1 (0.61) | L3MBTL1DRD4DRD2MCHR1SIGMAR1 | |
| SCHEMBL8219766 | 0.89 | L3MBTL1 (0.69) | L3MBTL1DRD4MCHR1POLBSIGMAR1 | |
| SCHEMBL16995307 | 0.84 | HTR4 (0.45) | L3MBTL1 | |
| SCHEMBL8222417 | 0.81 | L3MBTL1 (0.50) | L3MBTL1 | |
| SCHEMBL1286719 | 0.78 | L3MBTL1 (0.48) | L3MBTL1 | |
| SCHEMBL955461 | 0.78 | DYRK1A (0.54) | L3MBTL1 | |
| SCHEMBL8224789 | 0.78 | L3MBTL1 (0.49) | L3MBTL1 | |
| SCHEMBL955297 | 0.78 | DYRK1A (0.54) | L3MBTL1 | |
| SCHEMBL953496 | 0.78 | DYRK1A (0.51) | L3MBTL1 | |
| SCHEMBL8226784 | 0.77 | L3MBTL1 (0.48) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1845973-B1 | PHARMACEUTICAL COMPOUNDS | ASTEX THERAPEUTICS LTD (GB) | 2015-08-12 | — | — | EP | disclosed |