Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 3/20 | 0.36 |
| ▸ | ADH1A | P07327 | 3/20 | 0.36 |
| ▸ | ADH7 | P40394 | 3/20 | 0.36 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.34 |
| ▸ | KDM5A | P29375 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | ADH1C | P00326 | 2/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.33 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.33 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | ADH4 | P08319 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | EYA2 | O00167 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | ACE | P12821 | 1/20 | 0.32 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18938102 | 0.92 | CAMK2A (0.32) | ADH1BADH1AADH7PRMT1KDM5A | |
| SCHEMBL16995353 | 0.91 | ADH1B (0.43) | ADH1BADH1AADH7KDM5AADH1C | |
| SCHEMBL16995356 | 0.88 | ADH1B (0.40) | ADH1BADH1AADH7PRMT1KDM5A | |
| SCHEMBL19059591 | 0.86 | BLM (0.42) | BLMPMP22 | |
| SCHEMBL20418911 | 0.85 | BLM (0.37) | CYP2C19BLMPMP22 | |
| SCHEMBL16995373 | 0.80 | KDM5A (0.45) | ADH1BADH1AADH7KDM5AADH1C | |
| SCHEMBL842029 | 0.79 | — | — | |
| SCHEMBL163128 | 0.78 | LMNA (0.53) | KDM5ALMNAKDM4CALKBH5SUCNR1 | |
| SCHEMBL16995384 | 0.77 | PAOX (0.50) | ADH1BADH1AADH7KDM5AADH1C | |
| SCHEMBL8604932 | 0.77 | LMNA (0.36) | PRMT1KDM5ALMNAKDM4CALKBH5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2576586-B1 | C-28 AMIDES OF MODIFIED C-3 BETULINIC ACID DERIVATIVES AS HIV MATURATION INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2015-08-12 | — | — | EP | disclosed |