Sugi Predict

Sugi Predict / Compounds / SCHEMBL16996014

SCHEMBL16996014

SCHEMBL16996014

c1ccc(-c2ccc(-c3ccc(N(c4ccc(-c5ccc6oc7ccccc7c6c5)cc4)c4ccc5c(c4)C(c4ccccc4)(c4ccccc4)c4ccccc4-5)cc3)cc2)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PLA2G2A P14555 4/20 0.37
▸ PLA2G4A P47712 4/20 0.37
▸ HSP90AA1 P07900 1/20 0.33
▸ HSP90AB1 P08238 1/20 0.33
▸ PLA2G10 O15496 1/20 0.33
▸ PDK2 Q15119 1/20 0.33
▸ KDM4E B2RXH2 2/20 0.33
▸ MEN1 O00255 2/20 0.33
▸ MAPT P10636 2/20 0.33
▸ KMT2A Q03164 2/20 0.33
▸ SMN1; SMN2 Q16637 2/20 0.33
▸ NPC1 O15118 1/20 0.33
▸ ALDH1A1 P00352 1/20 0.33
▸ HPGD P15428 1/20 0.33
▸ RAB9A P51151 1/20 0.33
▸ LMNA P02545 1/20 0.31
▸ OPRK1 P41145 1/20 0.31
▸ AHR P35869 1/20 0.30
▸ PIM1 P11309 1/20 0.30
▸ CSNK2A2 P19784 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16996016 1.00 PLA2G2A (0.37) PLA2G2APLA2G4AHSP90AA1HSP90AB1PLA2G10
SCHEMBL16996054 0.99 PLA2G2A (0.35) PLA2G2APLA2G4AHSP90AA1HSP90AB1PLA2G10
SCHEMBL16996003 0.99 PLA2G2A (0.35) PLA2G2APLA2G4AHSP90AA1HSP90AB1PLA2G10
SCHEMBL17806854 0.98 PLA2G2A (0.36) PLA2G2APLA2G4AHSP90AA1HSP90AB1PLA2G10
SCHEMBL21559063 0.98 PLA2G2A (0.36) PLA2G2APLA2G4AHSP90AA1HSP90AB1PLA2G10
SCHEMBL17804868 0.98 PLA2G2A (0.34) PLA2G2APLA2G4AHSP90AA1HSP90AB1PLA2G10
SCHEMBL16996334 0.98 PLA2G2A (0.34) PLA2G2APLA2G4AHSP90AA1HSP90AB1PLA2G10
SCHEMBL9916315 0.98 PLA2G2A (0.34) PLA2G2APLA2G4AHSP90AA1HSP90AB1PLA2G10
SCHEMBL16996004 0.98 PLA2G2A (0.34) PLA2G2APLA2G4AHSP90AA1HSP90AB1PLA2G10
SCHEMBL16996207 0.97 PLA2G2A (0.35) PLA2G2APLA2G4AHSP90AA1HSP90AB1PLA2G10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220285620-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2022-09-08 — — US disclosed
US-11362279-B2 Aromatic amine derivative, and organic electroluminescent element using same IDEMITSU KOSAN CO., LTD. (JP) 2022-06-14 — — US disclosed
US-20200321526-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO., LTD (JP) 2020-10-08 — — US disclosed
US-20200313090-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2020-10-01 — — US disclosed
US-20180226601-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, ILLUMINATION DEVICE, DISPLAY DEVICE, AND MIXED MATERIAL IDEMITSU KOSAN CO., LTD. (JP) 2018-08-09 — — US disclosed
US-20180226601-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, ILLUMINATION DEVICE, DISPLAY DEVICE, AND MIXED MATERIAL IDEMITSU KOSAN CO., LTD. (JP) 2018-08-09 — — US disclosed
US-10014477-B2 Aromatic amine derivative, and organic electroluminescent element using same IDEMITSU KOSAN CO., LTD. (JP) 2018-07-03 — — US disclosed
US-20180123043-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2018-05-03 — — US disclosed
US-20150243891-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2015-08-27 — — US disclosed
US-20150243891-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2015-08-27 — — US disclosed
US-20150228899-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2015-08-13 — — US disclosed
US-20150228899-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2015-08-13 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200313090-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME ASH2L, EHMT2, H1-2 PLA2G2A 2889/4885PLA2G4A 3687/4885HSP90AA1 3951/4885
US-20220285620-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME ASH2L, EHMT2, H1-2 PLA2G2A 2889/4885PLA2G4A 3687/4885HSP90AA1 3951/4885
US-20180123043-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME ASH2L, EHMT2, H1-2 PLA2G2A 2889/4885PLA2G4A 3687/4885HSP90AA1 3951/4885
US-11362279-B2 Aromatic amine derivative, and organic electroluminescent element using same ASH2L, EHMT2, H1-2 PLA2G2A 2889/4885PLA2G4A 3687/4885HSP90AA1 3951/4885
US-20150243891-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME ASH2L, EHMT2, H1-2 PLA2G2A 2889/4885PLA2G4A 3687/4885HSP90AA1 3951/4885
US-10014477-B2 Aromatic amine derivative, and organic electroluminescent element using same ASH2L, EHMT2, H1-2 PLA2G2A 2889/4885PLA2G4A 3687/4885HSP90AA1 3951/4885
US-20180226601-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, ILLUMINATION DEVICE, DISPLAY DEVICE, AND MIXED MATERIAL TMEM109, L1CAM, CD99 PLA2G2A 3428/4885PLA2G4A 4261/4885HSP90AA1 4443/4885
US-20200321526-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME ASH2L, EHMT2, H1-2 PLA2G2A 2889/4885PLA2G4A 3687/4885HSP90AA1 3951/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.